Indicate the pure opioid antagonist which has a half-life of 10 hours:

Correct Answer: B

Rationale: The correct answer is B: Naltrexone. Naltrexone is a pure opioid antagonist with a half-life of 10 hours, making it the most appropriate choice. Naloxone (A) is a short-acting opioid antagonist used for emergency overdose situations. Tramadol (C) is a weak opioid agonist with additional effects on serotonin and norepinephrine reuptake. Pentazocine (D) is a mixed opioid agonist-antagonist. Therefore, only Naltrexone fits the criteria of a pure opioid antagonist with a 10-hour half-life.

Correct Answer: C

Rationale: Rationale: C: Both MAO inhibitors and tricyclic antidepressants increase levels of biogenic amines like serotonin, norepinephrine, and dopamine by inhibiting their reuptake or breakdown. A: Both act presynaptically by inhibiting the reuptake of neurotransmitters, not postsynaptically. B: Only MAO inhibitors interact with certain foods to cause hypertensive crisis, not tricyclic antidepressants. D: Tricyclic antidepressants are used for bipolar depression, not the manic phase.

Correct Answer: D

Rationale: The correct answer is D (All of the above). Piracetam is used for senile dementia due to its cognitive-enhancing effects. It is also used for asthenia (weakness/fatigue) as it helps improve energy levels. Additionally, piracetam is used in chronic alcoholism to aid in cognitive function and reduce neurotoxic effects. Therefore, all three options are correct based on the different therapeutic benefits of piracetam. The other choices are incorrect because each condition mentioned can be treated with piracetam, making option D the most comprehensive and accurate answer.

Correct Answer: D

Rationale: Cocaine may cause powerful vasoconstrictive reactions, leading to myocardial infarctions due to increased blood pressure and heart strain. It can also result in multiple brain perfusion defects due to restricted blood flow. Additionally, cocaine use during pregnancy can lead to spontaneous abortion due to its harmful effects on fetal development. Therefore, the correct answer is D, as all of these adverse effects are associated with cocaine use. Choices A, B, and C are incorrect as they do not cover the full spectrum of potential harm caused by cocaine.

Correct Answer: B

Rationale: The correct answer is B: Isoprenaline. Isoprenaline is a non-selective beta2-adrenomimic because it stimulates both beta1 and beta2 adrenergic receptors. This leads to effects on both the heart and lungs. Salbutamol, Salmeterol, and Terbutaline are selective beta2-adrenomimics, meaning they primarily target beta2 receptors in the lungs, resulting in bronchodilation without significant effects on the heart. Therefore, they do not belong to the category of non-selective beta2-adrenomimics like Isoprenaline.