Indicate the drug that induces parkinsonian syndromes:

Correct Answer: A

Rationale: Certainly! Chlorpromazine is the correct answer as it is a typical antipsychotic known to induce parkinsonian syndromes as a side effect due to its dopamine-blocking properties. This leads to a decrease in dopamine levels and imbalance in the basal ganglia function, resulting in symptoms resembling Parkinson's disease. Diazepam, Triazolam, and Carbamazepine do not typically induce parkinsonian syndromes as they do not directly affect dopamine levels or basal ganglia function.

Correct Answer: C

Rationale: The correct answer is C: Clopheline. Clopheline is a centrally acting alpha-2 adrenergic agonist known for its analgesic effects by modulating pain perception in the central nervous system. Reserpine (A) is not an analgesic drug but rather a monoamine depletor. Propranolol (B) is a beta-blocker primarily used for cardiac conditions, not for its analgesic properties. Prazosin (D) is an alpha-1 adrenergic antagonist mainly used for hypertension and not known for its analgesic effects. Therefore, the correct answer is C as it directly acts on the central nervous system to provide analgesia.

Correct Answer: C

Rationale: The correct answer is C: Moclobemide. Moclobemide is a selective short-acting MAO-A inhibitor, which means it specifically targets the MAO-A enzyme, leading to increased levels of serotonin and norepinephrine. This helps alleviate symptoms of depression. Maprotiline (A) is a tetracyclic antidepressant, Amitriptyline (B) is a tricyclic antidepressant, and Selegiline (D) is a MAO-B inhibitor used for Parkinson's disease, not for depression. Therefore, C is the correct answer as it matches the criteria of being a selective short-acting MAO-A inhibitor.

Correct Answer: D

Rationale: The correct answer is D: Significant abuse potential. Cordiamine is primarily used as a cardiac analeptic, respiratory analeptic, and coronarodilatator, meaning it stimulates cardiac and respiratory functions and dilates coronary blood vessels. There is no evidence or indication that cordiamine has significant abuse potential. It is not a psychoactive substance and does not produce euphoria or addiction. Therefore, option D is the correct answer as it does not align with the principal properties of cordiamine.

Correct Answer: B

Rationale: Step 1: Diazepam is a benzodiazepine known for its high abuse potential due to its sedative and hypnotic effects. Step 2: Benzodiazepines like diazepam can lead to physical and psychological dependence. Step 3: Buspirone is a non-benzodiazepine anxiolytic with low abuse potential. Step 4: Phenobarbital is a barbiturate with significant abuse potential but generally less than benzodiazepines. Step 5: Zolpidem is a non-benzodiazepine sedative-hypnotic with lower abuse potential compared to benzodiazepines like diazepam.