ATI RN
Pharmacology of Drugs Acting on Cardiovascular System Questions
Question 1 of 5
Indicate the drug belonging to fibrinoliytic inhibitors:
Correct Answer: A
Rationale: Step-by-step rationale for why Aminocaproic acid (A) is the correct answer: 1. Aminocaproic acid is a fibrinolytic inhibitor that prevents the breakdown of blood clots. 2. It works by inhibiting the activation of plasminogen to plasmin, which is essential for clot dissolution. 3. Therefore, Aminocaproic acid belongs to the class of fibrinolytic inhibitors. Summary of why the other choices are incorrect: - Ticlopidine (B) is a platelet aggregation inhibitor, not a fibrinolytic inhibitor. - Streptokinase (C) is a fibrinolytic drug that promotes clot breakdown, not an inhibitor. - Vitamin K (D) is essential for clotting factors synthesis, not a fibrinolytic inhibitor.
Question 2 of 5
The reason of beta-blockers administration for hypertension treatment is:
Correct Answer: C
Rationale: The correct answer is C: Decreasing of heart work. Beta-blockers reduce blood pressure by decreasing the heart's workload through blocking the effects of adrenaline on the heart, resulting in lowered heart rate and force of contraction. This reduces the amount of blood pumped by the heart, leading to decreased blood pressure. The other choices are incorrect because: A: Peripheral vasodilatation - Beta-blockers actually cause vasoconstriction, not vasodilatation. B: Diminishing of blood volume - Beta-blockers do not directly affect blood volume. D: Depression of vasomotor center - Beta-blockers primarily act on the heart, not the vasomotor center.
Question 3 of 5
The hypothalamic control exists for the thyroid gland. This consideration is:
Correct Answer: A
Rationale: The correct answer is A: TRUE. The hypothalamus secretes thyrotropin-releasing hormone (TRH) which stimulates the anterior pituitary to release thyroid-stimulating hormone (TSH), which in turn stimulates the thyroid gland to produce thyroid hormones. This demonstrates the hypothalamic control over the thyroid gland. Choices B, C, and D are incorrect because the hypothalamus does indeed play a crucial role in regulating the thyroid gland, making the statement true rather than false, all-encompassing, or none at all.
Question 4 of 5
Main complications of insulin therapy include the following:
Correct Answer: D
Rationale: The correct answer is D, "All of the above." Insulin therapy can lead to hypoglycemia due to excessive insulin dosage, insulin allergy in some rare cases, and lipodystrophy at injection sites from repeated injections. Each complication is a potential risk of insulin therapy, making all choices relevant. Therefore, option D is the correct answer as it encompasses all possible complications. Choices A, B, and C individually address specific complications but do not cover the full scope of potential issues associated with insulin therapy, making them incorrect in this context.
Question 5 of 5
The following statements concerning aspirin are true, EXCEPT:
Correct Answer: C
Rationale: Rationale: C: Aspirin inhibits phospholipase A2. This statement is FALSE. Aspirin does not directly inhibit phospholipase A2. The correct answer is C. Summary: A: TRUE - Aspirin irreversibly inhibits COX. B: TRUE - Aspirin interferes with the chemical mediators of the kallikrein system. D: TRUE - Aspirin inhibits thromboxane A2 formation.