ATI RN
Cardiovascular Drugs Pharmacology PPT Questions
Question 1 of 5
Indicate the antidepressant agent,which is a phenyltolylpropylamine derivative:
Correct Answer: C
Rationale: The correct answer is C: Fluoxetine. Fluoxetine is a phenyltolylpropylamine derivative due to its chemical structure. It falls under the class of selective serotonin reuptake inhibitors (SSRIs), making it an antidepressant agent. Paroxetine (A) is an SSRI but not a phenyltolylpropylamine derivative. Maprotiline (B) is a tetracyclic antidepressant, not a phenyltolylpropylamine derivative. Amitriptyline (D) is a tricyclic antidepressant, not a phenyltolylpropylamine derivative. Therefore, the correct answer is C.
Question 2 of 5
Indicate the anesthetic,which is an inhibitor of NMDA glutamate receptors:
Correct Answer: C
Rationale: Step-by-step rationale for why Ketamine (choice C) is the correct answer: 1. Ketamine is a known NMDA receptor antagonist, blocking the receptor's activity. 2. By inhibiting NMDA receptors, Ketamine produces dissociative anesthesia. 3. Thiopental (A) is a GABA agonist, Halothane (B) is a volatile anesthetic, and Sevoflurane (D) enhances GABA activity, not acting on NMDA receptors.
Question 3 of 5
Zafirlucast prevents aspirin-sensitive asthma. This consideration is:
Correct Answer: A
Rationale: Step-by-step rationale: 1. Zafirlukast is a leukotriene receptor antagonist used to treat asthma. 2. Aspirin-sensitive asthma is a condition triggered by aspirin and other NSAIDs. 3. Studies have shown that zafirlukast can prevent bronchoconstriction in aspirin-sensitive asthma. 4. Therefore, the statement that Zafirlukast prevents aspirin-sensitive asthma is TRUE. Summary: - Choice A is correct because zafirlukast has been proven to prevent aspirin-sensitive asthma. - Choice B is incorrect as evidence supports the effectiveness of zafirlukast. - Choice C is incorrect as not all choices are true. - Choice D is incorrect as the correct answer is A, making this choice incorrect.
Question 4 of 5
Which of the following substances is synthesized within vessel walls and inhibits thrombogenesis?
Correct Answer: B
Rationale: The correct answer is B: Prostacyclin (PGI2). Prostacyclin is synthesized within vessel walls and acts as a potent inhibitor of thrombogenesis by inhibiting platelet aggregation and promoting vasodilation. Thromboxane A2 (TXA2) (Choice A) is synthesized by platelets and promotes platelet aggregation. Prostaglandin E (PGE) (Choice C) is involved in various physiological processes but does not specifically inhibit thrombogenesis. Choice D is incorrect as Prostacyclin is indeed synthesized within vessel walls and inhibits thrombogenesis.
Question 5 of 5
This drug is a Class II antiarrhythmic drug:
Correct Answer: B
Rationale: The correct answer is B: Propranolol. Class II antiarrhythmics are beta-blockers, which work by blocking the effects of adrenaline on the heart. Propranolol specifically is a non-selective beta-blocker that reduces heart rate and blood pressure, making it effective in treating certain types of arrhythmias. Flecainide (A) is a Class IC antiarrhythmic, Lidocaine (C) is a Class IB antiarrhythmic, and Verapamil (D) is a Class IV antiarrhythmic. These drugs have different mechanisms of action and are not classified as Class II antiarrhythmics.