Indicate the adrenoreceptor antagonist drug which is a rauwolfia alkaloid:

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Drugs for Cardiovascular Disease Questions

Question 1 of 5

Indicate the adrenoreceptor antagonist drug which is a rauwolfia alkaloid:

Correct Answer: C

Rationale: The correct answer is C: Reserpine. Reserpine is a rauwolfia alkaloid acting as an adrenoreceptor antagonist by inhibiting the storage of norepinephrine and serotonin in vesicles. Prazosin (A) is an alpha-1 adrenergic receptor antagonist, Propranolol (B) is a non-selective beta-adre, Phentolamine (D) is a non-selective alpha-adrenergic receptor antagonist, making them all incorrect choices.

Question 2 of 5

Which of the following neurotransmitters is involved in Parkinson′s disease?

Correct Answer: C

Rationale: The correct answer is C: Dopamine. Parkinson's disease is characterized by a loss of dopamine-producing neurons in the brain. Dopamine is crucial for controlling movement and coordination, and its deficiency leads to symptoms of Parkinson's. Acetylcholine (Choice A) is not primarily involved in Parkinson's disease, and excess glutamate (Choice B) can actually be harmful in neurodegenerative disorders. Choice D is incorrect as acetylcholine and glutamate are not directly related to Parkinson's disease.

Question 3 of 5

Which of the following opioid analgesics is used in combination with droperidol in neuroleptanalgesia?

Correct Answer: C

Rationale: The correct answer is C: Fentanyl. Fentanyl is used in combination with droperidol in neuroleptanalgesia due to its fast onset of action and potent analgesic effects, making it an ideal choice for sedation and analgesia during procedures. Morphine (choice A) is not typically used in neuroleptanalgesia due to its slower onset of action and shorter duration. Buprenorphine (choice B) is a partial opioid agonist and is not commonly used in neuroleptanalgesia. Lastly, the duplicate choice D (Morphine) is incorrect for the same reasons mentioned earlier. In summary, Fentanyl is the preferred choice for neuroleptanalgesia due to its rapid onset and potent analgesic properties compared to the other options.

Question 4 of 5

Analgin usefulness is limited by:

Correct Answer: A

Rationale: The correct answer is A: Agranulocytosis. Analgin can cause a serious side effect called agranulocytosis, which is a condition where the bone marrow stops producing enough white blood cells, leaving the body vulnerable to infections. This limits the usefulness of Analgin as the risk of developing agranulocytosis outweighs its benefits. Summary of other choices: B: Erosions and gastric bleeding - While Analgin can cause gastrointestinal side effects like erosions and bleeding, these are not as severe or limiting as agranulocytosis. C: Methemoglobinemia - Although Analgin can lead to methemoglobinemia, it is a rare side effect compared to agranulocytosis. D: Hearing impairment - There is no significant evidence linking Analgin to hearing impairment, making this choice incorrect.

Question 5 of 5

Which of the following antidepressants is an unselective MAO blocker and produces extremely long-lasting inhibition of the enzyme?

Correct Answer: B

Rationale: The correct answer is B: Tranylcypramine. Tranylcypramine is an unselective MAO blocker, inhibiting both MAO-A and MAO-B, leading to long-lasting enzyme inhibition. Moclobemide (A) is a reversible MAO-A inhibitor. Selegiline (C) is a selective MAO-B inhibitor. Fluoxetine (D) is a selective serotonin reuptake inhibitor (SSRI) and does not inhibit MAO enzymes. Therefore, Tranylcypramine is the correct choice for producing long-lasting MAO inhibition.

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