ATI RN
Safety Pharmacology Across the Lifespan ATI Quizlet Questions
Question 1 of 5
Indicate an antiseizure drug, inhibiting central effects of excitatory amino acids:
Correct Answer: B
Rationale: Lamotrigine inhibits the release of excitatory amino acids like glutamate by blocking sodium channels and reducing presynaptic neurotransmitter release. Ethosuximide targets calcium channels, Diazepam enhances GABA, and Tiagabine increases GABA availability, none of which directly inhibit excitatory amino acids.
Question 2 of 5
The dose-related adverse effect of ethosuximide is:
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
The pathophysiologic basis for antiparkinsonism therapy is:
Correct Answer: A
Rationale: Antiparkinsonism therapy targets the selective loss of dopaminergic neurons in the substantia nigra, which disrupts the balance between dopamine and acetylcholine in the basal ganglia. Treatments aim to restore dopamine levels or reduce cholinergic overactivity, making 'A selective loss of dopaminergic neurons' the correct pathophysiological basis.
Question 4 of 5
Which of the following preparations combines carbidopa and levodopa in a fixed proportion?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
Indicate selective catechol-O-methyltransferase inhibitor, which prolongs the action of levodopa by diminishing its peripheral metabolism:
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.