ATI RN
Pharmacology Cardiovascular Drugs Study Guide Questions
Question 1 of 5
Indicate a general tone-increasing drug,which is an agent of animal origin?
Correct Answer: A
Rationale: Step-by-step rationale: 1. Pantocrin is a general tone-increasing drug. 2. Pantocrin is derived from animal sources. 3. It is known to have stimulating effects. 4. As an agent of animal origin, Pantocrin fits the criteria. Summary: B: Amphetamine is a synthetic drug, not of animal origin. C: Sydnocarb is a synthetic drug, not of animal origin. D: Camphor is a natural substance but not a general tone-increasing drug.
Question 2 of 5
Which of the following inhaled anesthetics can produce hepatic necrosis?
Correct Answer: C
Rationale: The correct answer is C: Halothane. Halothane can produce hepatic necrosis due to its metabolite, trifluoroacetic acid. This metabolite can lead to liver damage in susceptible individuals. Other choices, A (Sevoflurane), B (Desflurane), and D (Nitrous oxide) do not typically cause hepatic necrosis. Sevoflurane and Desflurane are not metabolized to toxic compounds that affect the liver, and Nitrous oxide is not known to cause hepatic necrosis. Therefore, the correct answer is C because of the specific hepatotoxic effects associated with Halothane.
Question 3 of 5
Indicate the drug that cause metabolic alkalosis:
Correct Answer: A
Rationale: The correct answer is A: Sodium bicarbonate. Sodium bicarbonate causes metabolic alkalosis by increasing bicarbonate levels in the body, leading to an excess of base. This can occur in conditions like overdose or prolonged use. B: Cimetidine is an H2 receptor antagonist that can cause metabolic acidosis, not alkalosis. C: Pepto-Bismol contains bismuth subsalicylate and can cause metabolic acidosis. D: Carbenoxolone is a drug that can cause metabolic alkalosis.
Question 4 of 5
Mechanism of urokinase action is an inhibition of Thromboxane A2. This statement is:
Correct Answer: B
Rationale: The correct answer is B: FALSE. Urokinase is a thrombolytic agent that activates plasminogen to plasmin, which dissolves blood clots. It does not inhibit Thromboxane A2. Thromboxane A2 is involved in platelet aggregation and vasoconstriction. Choices A, C, and D are incorrect because urokinase does not inhibit Thromboxane A2.
Question 5 of 5
Verapamil has a significant effect on automaticity in the SA node It’s:
Correct Answer: A
Rationale: Verapamil is a calcium channel blocker that slows the influx of calcium ions in cardiac cells, leading to a decrease in automaticity in the SA node. This results in a decrease in heart rate. Therefore, choice A is correct. Choice B is incorrect because verapamil does affect automaticity. Choices C and D are incorrect as they do not accurately reflect the specific effect of verapamil on automaticity in the SA node.