Increases vascular permeability

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Pediatric Immunizations NCLEX Questions Questions

Question 1 of 4

Increases vascular permeability

Correct Answer: B

Rationale: Histamine, released by mast cells, increases vascular permeability, aiding immune cell infiltration to the site of infection.

Question 2 of 4

Which of the following subunit vaccines is recommended for children but not adults?

Correct Answer: B

Rationale: Hib vaccine is routinely given to children to prevent meningitis, not typically required for adults.

Question 3 of 4

A child presents with recurrent infections with bacteria, fungi, and viruses. The resident asks the attending physician about IL-2R gamma chain mutations, as the patient is a male. The attending physician makes a diagnosis and begins writing orders for bone marrow transplantation and possible gene therapy. Which of the following does the patient have?

Correct Answer: D

Rationale: SCID, often X-linked due to IL-2Rγ mutations, causes severe infections and requires bone marrow transplantation.

Question 4 of 4

A patient presents with complaints of dark urine in the morning that clears up partially during the day. Lab work reveals hemolytic anemia, thrombosis in large vessels, and a deficiency in Hematopoiesis. Which of the following is the most likely?

Correct Answer: D

Rationale: PNH causes hemolytic anemia (dark urine), thrombosis, and bone marrow failure due to complement-mediated cell destruction.

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