Increase Fe & normal TIBC are found in:

Correct Answer: C

Rationale: The correct answer is C: rheumatoid arthritis. In rheumatoid arthritis, chronic inflammation can lead to anemia of chronic disease, causing increased levels of serum iron (Fe) due to decreased iron utilization and normal Total Iron Binding Capacity (TIBC). Thalassemia major (A) would show decreased TIBC due to iron overload. Haemosiderosis (B) would show increased Fe and TIBC due to iron overload. Disseminated malignancy (D) may show decreased Fe and TIBC due to anemia of chronic disease or other factors.

Correct Answer: B

Rationale: Cooley's anemia is another term for thalassemia major, a genetic disorder characterized by abnormal hemoglobin production leading to severe anemia. The correct answer is B because Cooley's anemia specifically refers to thalassemia major. Sickle cell anemia (A) is a different genetic disorder caused by abnormal hemoglobin shape. High ESR (C) is a nonspecific marker of inflammation and does not directly relate to Cooley's anemia. Aplastic anemia (D) is a condition where the bone marrow does not produce enough blood cells, not related to Cooley's anemia.

Correct Answer: C

Rationale: Step-by-step rationale: 1. Chronic Myeloid Leukemia (CML) primarily involves the bone marrow and blood, not the liver, spleen, or lymph nodes. 2. Hepato-splenomegaly with lymphadenopathy are commonly seen in Acute Lymphoblastic Leukemia (ALL) and lymphoma. 3. Disseminated TB can cause hepato-splenomegaly but typically does not present with lymphadenopathy. Therefore, C (CML) is the correct answer as it does not typically present with the described findings.

Correct Answer: B

Rationale: The correct answer is B: 3-4 days. The half-life of a substance is the time it takes for half of the original amount to decay. In this case, since the half-life of platinum is 3-4 days, it means that after 3-4 days, half of the initial amount of platinum will have decayed. This answer is correct because it accurately represents the time frame for platinum decay. The other choices are incorrect because they do not correspond to the known half-life of platinum. Choice A (1-2 days), C (5-6 days), and D (7-8 days) are outside the typical half-life range for platinum, making them incorrect options.

Correct Answer: A

Rationale: The correct answer is A: Monitoring for infection. Acute leukemia patients are at high risk for infections due to compromised immune function. Infection is the most common cause of death among leukemia patients. Regular monitoring for signs of infection, such as fever and abnormal white blood cell counts, is crucial for early detection and treatment. Option B, monitoring nutritional status, is important but not the most direct cause of death in leukemia patients. Option C, monitoring electrolyte levels, is important but not as directly related to the cause of death in leukemia patients. Option D, monitoring liver function, is not the most common cause of death in leukemia patients and is not directly related to leukemia complications.