In which of the following GIT infections, the bacteria adhere to the intestine wall and damage the microvilli:

Correct Answer: A

Rationale: The correct answer is A: Enteropathogenic E. Coli (EPEC). EPEC bacteria adhere to the intestine wall using a protein called intimin, leading to microvilli damage. This attachment disrupts the normal absorption function of the intestine. Summary of why other choices are incorrect: B: Enterohemorrhagic E. Coli (EHEC) primarily causes bloody diarrhea and does not specifically target microvilli. C: Enterotoxigenic E. Coli (ETEC) produces toxins that lead to watery diarrhea but does not directly target microvilli. D: Enteroinvasive E. Coli (EIEC) invades and replicates within intestinal cells, causing inflammatory diarrhea, but does not specifically damage microvilli.

Correct Answer: A

Rationale: The correct answer is A: IgG. IgG is the most abundant class of immunoglobulins in the body, constituting about 75% of total immunoglobulins. IgG plays a crucial role in long-term immunity, neutralizing toxins, and enhancing phagocytosis. IgE is involved in allergic reactions, IgD is mainly found on B cells and functions as a receptor, and IgM is the first antibody produced in response to an infection but is less abundant compared to IgG. Therefore, IgG is the correct choice based on its abundance and diverse functions in the immune system.

Correct Answer: C

Rationale: The correct answer is C, both A and B. Clostridium botulinum and Bacillus anthracis are both capable of forming spores, which are a protective mechanism that allows them to survive harsh conditions. Clostridium botulinum causes botulism and forms spores in anaerobic environments, while Bacillus anthracis causes anthrax and forms spores in aerobic environments. Therefore, both choices A and B are correct. Choice D is incorrect as it contradicts the fact that both bacteria are capable of forming spores.

Correct Answer: B

Rationale: The correct answer is B: Macrolides. Listeriosis is typically treated with antibiotics such as Penicillin and ampicillin due to their effectiveness against Listeria monocytogenes. Macrolides, on the other hand, are not first-line agents for listeriosis treatment. They are less effective in treating this bacterial infection compared to Penicillin and ampicillin. Cephalosporins may also be less effective against Listeria monocytogenes compared to Penicillin and ampicillin. Choice D is incorrect as Macrolides are not suitable for listeriosis treatment.

Correct Answer: D

Rationale: The correct answer is D because the catarrhal stage of whooping cough is characterized by mild respiratory symptoms such as mild coughing, sneezing, or a runny nose. During this stage, the cough may start to worsen but is not yet severe. A: Incorrect - Decrease in paroxysms of coughing is not seen in the catarrhal stage; it occurs later in the paroxysmal stage. B: Incorrect - Subsequent respiratory infection for many months after the onset of pertussis is not a characteristic of the catarrhal stage. C: Incorrect - Uncontrollable coughing followed by a high pitched 'whoop' sound is typical of the paroxysmal stage, not the catarrhal stage.

Correct Answer: A

Rationale: The correct answer is A because protozoan emerging and reemerging diseases fall under Group I according to the classification of infectious diseases by the Centers for Disease Control and Prevention (CDC). Group I includes diseases caused by newly identified or known infectious agents that have increased in incidence or geographic range. Choice B (Group II) includes diseases that have re-emerged due to antimicrobial resistance or lack of previous vaccination. Choice C (Group III) encompasses diseases that can be transmitted from animals to humans, and choice D (Group IV) includes diseases that are caused by re-introduction of eradicated pathogens.

Correct Answer: C

Rationale: Rationale for choice C (Strep. pneumoniae): 1. Strep. pneumoniae is a common cause of bacterial meningitis. 2. It is a leading pathogen responsible for meningitis in adults and children. 3. It can invade the bloodstream and reach the meninges, causing inflammation. 4. Treatment guidelines often include antibiotics effective against Strep. pneumoniae. Summary of why other choices are incorrect: A. Staph. aureus is not a common cause of meningitis. B. Strep. pyogenes typically causes streptococcal infections but not meningitis. D. "None of the above" is incorrect as Strep. pneumoniae can cause meningitis.

Correct Answer: D

Rationale: The correct answer is D: Propionibacterium acnes. This bacterium plays a key role in acne formation by colonizing hair follicles, leading to inflammation and acne lesions. It produces fatty acids that contribute to the development of acne. Staphylococcus aureus (A) and Staphylococcus epidermidis (B) are not directly linked to acne. Streptococcus pyogenes (C) is associated with skin infections but not acne. In summary, Propionibacterium acnes is the primary bacterium responsible for acne due to its ability to induce inflammation and follicular blockages.

Correct Answer: A

Rationale: The correct answer is A: Bordetella pertussis. This bacterium is known for causing whooping cough due to its ability to produce toxins that damage the respiratory tract, leading to severe coughing fits. Clostridium tetani causes tetanus, Haemophilus influenzae can cause respiratory infections but not whooping cough, and Staphylococcus aureus is more commonly associated with skin infections. Therefore, A is the correct choice based on its specific association with the disease in question.