ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions
Question 1 of 5
In the treatment of congenital adrenal hyperplasia in which there is excess production of cortisol precursor, the purpose of administration of synthetic glucocorticoid is:
Correct Answer: D
Rationale: In CAH (choice D), synthetic glucocorticoids suppress ACTH, reducing adrenal precursor excess (e.g., 17-hydroxyprogesterone). Aldosterone (choice A), renal (choice B), and immune (choice C) effects aren't primary goals. ACTH suppression corrects the defect.
Question 2 of 5
Blockade of which of the following pairs of receptors likely mediated the adverse effect of olanzapine in the 37-year-old woman with a schizoaffective disorder?
Correct Answer: B
Rationale: The most likely receptors mediating the adverse effect of olanzapine in the 37-year-old woman are GABAergic and muscarinic receptors. Olanzapine, an atypical antipsychotic, can have side effects such as acute psychotic states and aggression, which may be due to its interaction with these receptors. Blocking GABAergic receptors can lead to disinhibition and agitation, while muscarinic receptor blockade can cause cognitive impairment and confusion, both of which could contribute to the patient's acute psychotic state and aggressive behavior.
Question 3 of 5
Which of the following are NOT correctly paired?
Correct Answer: D
Rationale: Buspirone (choice A), Alprazolam (choice B), and Baclofen (choice C) are correctly paired (anxiolytic, some antidepressant effect, less sedative muscle relaxant). Oxazepam (choice D), a benzodiazepine, isn't a TCA, making it the incorrect pair. This tests drug classification.
Question 4 of 5
Following is used in methanol poisoning
Correct Answer: C
Rationale: Ethanol competes with methanol for alcohol dehydrogenase preventing the formation of toxic metabolites.
Question 5 of 5
Hyperthyroidism can be treated by the following EXCEPT:
Correct Answer: A
Rationale: Carbimazole (choice A) and Propylthiouracil (choice D) treat hyperthyroidism by inhibiting thyroid hormone synthesis, Propranolol (choice C) manages symptoms. Carbamazepine (choice B), an anticonvulsant, is unrelated, making it the exception. This clarifies antithyroid therapy.