ATI RN
ABVD chemotherapy drugs Questions
Question 1 of 5
In the management of patients with AIDS, the sulfonamides are often used in combination with inhibitors of folate reductase. However, such combinations have minimal activity against
Correct Answer: D
Rationale: Trimethoprim-sulfamethoxazole has minimal activity against Treponema pallidum (syphilis), which requires penicillin or other drugs.
Question 2 of 5
A young female patient using an oral contraceptive is to be treated for pulmonary tuberculosis. She is advised to use an additional method of contraception since the efficacy of the oral agents is commonly decreased if her drug regimen includes
Correct Answer: D
Rationale: Rifampin induces hepatic enzymes (CYP450), reducing the efficacy of oral contraceptives by increasing their metabolism.
Question 3 of 5
This compound reduces the need for platelet transfusions in patients undergoing cancer chemotherapy
Correct Answer: C
Rationale: Interleukin-11 (not II as listed, likely a typo) stimulates thrombopoiesis, reducing the need for platelet transfusions in chemotherapy patients.
Question 4 of 5
Relative to Lugol's solution propylthouracil has
Correct Answer: D
Rationale: Propylthiouracil (PTU) has more sustained antithyroid activity than Lugol’s solution when used long-term, inhibiting thyroid hormone synthesis.
Question 5 of 5
Graft-versus-host (GVH) disease is associated primarily with which type of transplantation?
Correct Answer: C
Rationale: GVH disease is primarily associated with bone marrow transplantation due to donor immune cells attacking the recipient.