In the delivery room and after prolonged labor you received a newborn baby with central and peripheral cyanosis, heart rate 90/min, weak cry, arms and legs well flexed, and withdrawal motion. The Apgar score is

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Pediatric Infectious Disease Practice Questions Questions

Question 1 of 5

In the delivery room and after prolonged labor you received a newborn baby with central and peripheral cyanosis, heart rate 90/min, weak cry, arms and legs well flexed, and withdrawal motion. The Apgar score is

Correct Answer: C

Rationale: Apgar: cyanosis (color=0), HR 90 (heart rate=1), weak cry (respiration=1), flexed (tone=2), withdrawal (reflex=2) totals 6 (C), reflecting moderate distress.

Question 2 of 5

Congenital toxoplasmosis occurs through vertical transmission of Toxoplasma gondii by transplacental transfer of the organism from the mother to the fetus. All the following statements are true EXCEPT

Correct Answer: D

Rationale: Toxoplasmosis treatment (A), transmission increase with gestation (B), acute infection (C), and severity decrease with gestation (E) are true. Reactivation (D) rarely causes fetal infection, making it false.

Question 3 of 5

Congenital CMV infection proved when CMV detected within the first

Correct Answer: A

Rationale: CMV detection within 3 weeks (A) confirms congenital infection, distinguishing it from postnatal acquisition, per diagnostic standards.

Question 4 of 5

A 3-week-old infant presented with poor feeding, maculopapular rash over the palms and soles and around the mouth, and bloody nasal discharge; on examination there are hepatosplenomegaly and lymphadenopathy; CBC reveals hemolytic anemia and thrombocytopenia. Of the following, the MOST likely diagnosis is

Correct Answer: A

Rationale: Rash on palms/soles, snuffles, hepatosplenomegaly, and anemia at 3 weeks point to congenital syphilis (A), unlike HSV (B), CMV (C), rubella (D), or toxoplasmosis (E) presentations.

Question 5 of 5

The unexplained additional risk factor for early-onset neonatal sepsis is

Correct Answer: A

Rationale: Male sex (A) is an unexplained risk factor for early-onset sepsis, beyond preterm birth (B), maternal fever (C), tachycardia (D), or PROM (E), per studies.

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