ATI RN
Pediatric Immunization NCLEX Questions Ricci Questions
Question 1 of 5
In the classical pathway, after the proteolysis of C3 complement pathway, which component is cleaved by C4bC2aC3b and initiate the formation of membrane attack complex
Correct Answer: A
Rationale: C5 is cleaved by C5 convertase (C4b2a3b) to initiate MAC formation.
Question 2 of 5
19-year-old college student develops a rash. She works part-time in a pediatric AIDS clinic. Her blood is drawn and tested for specific antibody to the chicken pox virus (varicella-zoster). Which of the following antibody classes would you expect to find if she is immune to chicken pox?
Correct Answer: A
Rationale: IgG indicates long-term immunity to past infections like chickenpox.
Question 3 of 5
Antigen presenting cells (APCs) are required for T-cell recognition of specific antigen and activation. APCs accomplish this task by presenting antigen in the context of which of the following molecules?
Correct Answer: C
Rationale: APCs present antigens on MHC molecules to T cells.
Question 4 of 5
A 9-month-old boy presented with recurrent attacks of diarrhea, thrush, and failure to thrive shortly after birth. You suspect immune deficiency. Of the following, the MOST common cause of this condition is
Correct Answer: C
Rationale: The symptoms (diarrhea, thrush, failure to thrive) suggest severe combined immunodeficiency (SCID), most commonly due to T-cell defects, which impair both cellular and humoral immunity.
Question 5 of 5
The treatment of choice for a 3-year-old boy with Wiskott-Aldrich syndrome is
Correct Answer: D
Rationale: Bone marrow or cord blood transplantation is curative for WAS, correcting the underlying genetic defect affecting immunity, platelets, and eczema.