ATI RN
Pediatric Immunization Test Questions Questions
Question 1 of 5
In the classical complement pathway, which of the following components is the initiating protein(s)?
Correct Answer: A
Rationale: C1 is the initiating protein in the classical pathway, binding to antibodies.
Question 2 of 5
Which of the following alerts the adaptive immune system to the presence of infection?
Correct Answer: D
Rationale: IL-12 bridges innate and adaptive immunity by activating T cells.
Question 3 of 5
Mast cell arachidonic acid metabolites include cyclo-oxygenase, which produces prostaglandins that stimulate and increase of smooth muscle in the gut and bronchi. Metabolites also include leukotrienes, which have a effect than prostaglandins.
Correct Answer: D
Rationale: Prostaglandins cause vasodilation and smooth muscle contraction, while leukotrienes have a faster, more potent effect on inflammation and constriction.
Question 4 of 5
Vaccines (natural exposure) is considered active immunotherapy and leads to the development of immunologic memory.
Correct Answer: A
Rationale: Active immunotherapy via vaccines stimulates the immune system to produce memory cells, conferring long-term immunity.
Question 5 of 5
Pathogens can evade the immune system through antigenic drift, which is a mutation that leaves existing antibodies and antigenic shift, which is a mutation that leaves existing antibodies
Correct Answer: A
Rationale: Antigenic drift involves minor mutations reducing antibody efficacy, while antigenic shift involves major changes rendering antibodies ineffective.