In the case of a Heparin overdose, which antidote would you give?

Correct Answer: D

Rationale: Heparin is an anticoagulant medication that can lead to excessive bleeding if overdosed. Protamine sulfate is the specific antidote for heparin overdose. It works by binding to heparin and neutralizing its anticoagulant effects. This helps to reverse the effects of heparin and prevent further bleeding complications. In cases of heparin overdose or when rapid reversal of heparin's anticoagulant effects is required, protamine sulfate should be administered. Naloxone is used as an antidote for opioid overdose, Ibutilide is a antiarrhythmic medication used for atrial fibrillation, and Methylphenidate is a stimulant medication used for ADHD.

Correct Answer: D

Rationale: Methyldopa (Aldomet) is commonly used for managing hypertension in pregnant women. It is considered safe during pregnancy and is often the first-line treatment for hypertension in pregnancy. Methyldopa acts by stimulating alpha-adrenergic receptors in the central nervous system, leading to a decrease in peripheral vascular resistance, which helps to lower blood pressure. Other antihypertensive drugs, such as Enalapril and Hydrochlorothiazide, are not recommended during pregnancy as they can cause harm to the fetus. Mannitol is a diuretic used for managing cerebral edema and intraocular pressure but is not typically used for hypertension in pregnancy. Therefore, Methyldopa is the preferred choice for managing hypertension in pregnant patients.

Correct Answer: A

Rationale: Chemotherapy-induced vomiting is primarily caused by the stimulation of neuroreceptors in the medulla oblongata, particularly the chemoreceptor trigger zone (CTZ). The CTZ is sensitive to chemical stimuli and responds to the presence of chemotherapy drugs by triggering the vomiting reflex. While irritation of the gastric mucosa can contribute to nausea, it is not the primary mechanism. Autonomic instability and inhibition of catecholamines are not directly related to chemotherapy-induced vomiting. Anti-emetic medications often target these neuroreceptors to prevent or reduce vomiting.

Correct Answer: C

Rationale: The most helpful test in determining the response to highly active antiretroviral therapy (HAART) in an HIV-positive client is a viral load test. A viral load test measures the amount of HIV in the blood by counting the number of copies of the virus present. Monitoring viral load levels over time provides vital information about how well the antiretroviral medications are working in suppressing the replication of the virus. A decrease in viral load indicates a positive response to the therapy, while an increase may suggest treatment failure or the development of drug resistance. Regular monitoring of viral load is a crucial aspect of managing HIV infection and assessing the effectiveness of antiretroviral therapy.

Correct Answer: C

Rationale: Tetracycline, a broad-spectrum antibiotic, requires specific administration instructions to ensure efficacy. It binds to divalent cations like calcium (in milk), magnesium (in antacids), and iron (in supplements), forming insoluble chelates that reduce absorption, rendering it ineffective. The instruction 'Do not take the medication with milk' is critical to avoid this interaction, ensuring therapeutic levels are achieved. Taking it with antacids or iron similarly impairs absorption, making these incorrect and potentially harmful suggestions. Decreasing vitamins is irrelevant, as vitamins don't typically interfere unless combined with minerals. This guidance aligns with tetracycline's pharmacokinetics, emphasizing timing away from meals or supplements containing these ions. Effective discharge teaching prevents treatment failure, especially for infections requiring consistent drug levels, making C the priority instruction for the client's understanding and adherence.