In the alternative complement pathway, this component molecule undergoes spontaneous activation, which creates a challenge for organ xenotransplantation.

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Pediatric Immune Disorder Test Questions Questions

Question 1 of 5

In the alternative complement pathway, this component molecule undergoes spontaneous activation, which creates a challenge for organ xenotransplantation.

Correct Answer: C

Rationale: C3 spontaneously activates in the alternative pathway, complicating xenotransplantation.

Question 2 of 5

Which of the following are early clinical signs of (septic) shock?

Correct Answer: D

Rationale: Septic shock is characterized by systemic vasodilation leading to hypotension and a compensatory increase in heart rate (tachycardia) to maintain perfusion.

Question 3 of 5

Which of the following is NOT true regarding eosinophils?

Correct Answer: D

Rationale: Eosinophils are not a major acidic/anionic protein; they are cells with granules containing cationic proteins like major basic protein.

Question 4 of 5

Which of the following live vaccines is recommended for children but not adults?

Correct Answer: A

Rationale: The live oral poliovirus vaccine is primarily recommended for children, with adults typically receiving inactivated polio vaccine.

Question 5 of 5

Which of the following diseases affect neutrophils?

Correct Answer: C

Rationale: CGD affects neutrophil function due to defective NADPH oxidase, impairing microbial killing.

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