In rare instances, B cells can be found that have two immunoglobulin light chain alleles, both of which are rearranged in frame, and can encode functional light chain proteins. Yet, on the surface of the B cell, only one of the two light chain proteins is detected in the membrane-bound immunoglobulin receptor. The reason these rare cells have two functional light chain rearrangements but only express one of the two light chains as part of the B-cell receptor is:

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Immune System Quiz Questions Questions

Question 1 of 5

In rare instances, B cells can be found that have two immunoglobulin light chain alleles, both of which are rearranged in frame, and can encode functional light chain proteins. Yet, on the surface of the B cell, only one of the two light chain proteins is detected in the membrane-bound immunoglobulin receptor. The reason these rare cells have two functional light chain rearrangements but only express one of the two light chains as part of the B-cell receptor is:

Correct Answer: B

Rationale: Allelic exclusion ensures one light chain pairs with heavy chain ; pseudogenes , transcription , or RAG don't explain this.

Question 2 of 5

Passive immunity depends upon

Correct Answer: B

Rationale: Passive immunity involves receiving pre-formed antibodies from another source, not self-production or cell transfer.

Question 3 of 5

HIV is a virus that is particularly difficult to eradicate

Correct Answer: C

Rationale: HIV's high mutation rate creates drug-resistant strains, complicating eradication, not its RNA genome, rare mutation, or size.

Question 4 of 5

Which molecule below is a fungal pathogen associated molecular pattern (PAMP)?

Correct Answer: C

Rationale: Zymosan, a fungal cell wall component, is a PAMP, unlike dsRNA (viral), LPS (bacterial), or CpG (bacterial DNA).

Question 5 of 5

Which of the following statements does not describe an antibody (Ab) effector function?

Correct Answer: B

Rationale: Antibodies don't form pores (complement does via MAC); they mediate ADCC, neutralization, opsonization, and complement activation.

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