In preparation for business trip abroad the doctor was prescribed a histoschizontocidal antimalarial drug as a personal means of disease prevention. What drug was given to the doctor?

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Question 1 of 9

In preparation for business trip abroad the doctor was prescribed a histoschizontocidal antimalarial drug as a personal means of disease prevention. What drug was given to the doctor?

Correct Answer: B

Rationale: The correct answer is B: Mefloquine. Mefloquine is a histoschizontocidal antimalarial drug commonly prescribed for prevention of malaria in travelers. It is effective against the liver stage of the malaria parasite, which is crucial for preventing the development of the disease. Chingamin (A) is not a commonly used antimalarial drug. Biseptol (C) is a combination antibiotic and is not effective against malaria parasites. Quinine (D) is primarily used for treating malaria, not preventing it, and it is not specifically histoschizontocidal.

Question 2 of 9

Planned mass vaccination of all newborn 5-7 day old children against tuberulosis plays an important role in tuberculosis prevention. In this case the following vaccine is applied:

Correct Answer: A

Rationale: The correct answer is A: BCG (Bacille Calmette-Guerin). BCG is the vaccine used for tuberculosis prevention, not only for newborns but also for older children and adults. BCG helps in protecting against severe forms of tuberculosis in infants. Diphteria and tetanus toxoids and pertussis vaccine (choice B) is for protection against diphtheria, tetanus, and pertussis, not tuberculosis. Diphtheria and tetanus anatoxin vaccine (choice C) provides protection against diphtheria and tetanus, not tuberculosis. Adsorbed diphtheria vaccine (choice D) is specifically for diphtheria, not tuberculosis. Therefore, the correct choice is A as it is the only vaccine related to tuberculosis prevention.

Question 3 of 9

A 23-year-old man developed a perforation in his hard palate, a dense formation with clear margins was detected in this area. After a surgery, microscopy of excised formation shows there a large focus of caseous necrosis surrounded with a granulation tissue with endovasculitis and a cellular infiltration consisting of lymphocytes and epithelioid cells with predominance of plasma cells. What is the most likely disease in this case?

Correct Answer: B

Rationale: The correct answer is B: Tuberculosis. The case describes a man with a perforation in the hard palate and features of caseous necrosis with granulation tissue, endovasculitis, and a cellular infiltration mainly of lymphocytes, epithelioid cells, and plasma cells. These findings are classic for tuberculosis infection, commonly seen in extrapulmonary sites like the oral cavity. Syphilis (choice A) typically presents with a painless ulcer and different histopathological features. Leprosy (choice C) presents with granulomas containing foamy macrophages. Scleroma (choice D) is caused by Klebsiella rhinoscleromatis and presents with chronic granulomatous inflammation.

Question 4 of 9

Which of the following does NOT describe Cephalosporins

Correct Answer: D

Rationale: The correct answer is D: interferes with protein synthesis. Cephalosporins are beta-lactam antibiotics that work by inhibiting bacterial cell wall synthesis, not protein synthesis. They are bactericidal and have a relatively broad spectrum of activity against various bacteria. Choice A, B, and C all describe characteristics of cephalosporins, making them incorrect options.

Question 5 of 9

A patient has got pain in the axillary area, rise of temperature developed 10 hours ago. On examination: shaky gait is evident, the tongue is coated with white deposit. The pulse is frequent. The painful lymphatic nodes are revealed in the axillary area. The skin over the lymph nodes is erythematous and glistering. What is the most probable diagnosis?

Correct Answer: B

Rationale: The correct answer is B: Acute purulent lymphadenitis. The symptoms described indicate an acute bacterial infection of the lymph nodes. The presence of painful lymph nodes, erythema, and shiny appearance of the skin overlying the nodes suggest an inflammatory process. The rise in temperature and frequent pulse indicate an active infection. The white-coated tongue may be a sign of systemic involvement. The shaky gait may indicate systemic toxicity. Bubonic plague (A) presents with buboes, not just painful lymph nodes. Lymphogranulomatosis (C) is a type of lymphoma and would not present with these acute bacterial infection symptoms. Anthrax (D) typically presents with a black eschar and is less likely in this context.

Question 6 of 9

The bacterial genome is typically composed of:

Correct Answer: C

Rationale: The correct answer is C: circular double-stranded DNA. Bacterial genomes are typically composed of circular double-stranded DNA due to its stability and efficient replication. Circular DNA allows for continuous replication without the need for telomeres present in linear DNA (choice B). Bacteria do not typically have double-stranded RNA genomes (choice A) as RNA is more commonly found in viruses. Single-stranded DNA (choice D) is not typically the main genetic material in bacteria, as it is less stable and less efficient for information storage compared to double-stranded DNA.

Question 7 of 9

Disinfection is:

Correct Answer: C

Rationale: Disinfection is the process of destroying the vegetative forms of microorganisms, but their spores may survive. This is why choice C is correct. The other choices are incorrect because: A: Disinfection does not necessarily target spore forms exclusively. B: While disinfection targets vegetative forms, it does not always eliminate spore forms. D: Disinfection is not primarily used for determining the effect of physical agents on microorganisms.

Question 8 of 9

Bacterial families have general:

Correct Answer: A

Rationale: The correct answer is A: Morphologic features. Bacterial families are classified based on their morphologic features such as shape, size, and arrangement. This classification helps in identifying and studying different bacterial species. Choice B, Geographic features, is incorrect as bacterial classification is not based on their geographic distribution. Choice C, Historical features, is incorrect as it does not play a role in the classification of bacterial families. Choice D, Physiologic features, is also incorrect as physiological characteristics are used for further classification within bacterial families, not as a general characteristic.

Question 9 of 9

A 28 y.o. patient without permanent residence was admitted to the hospital with the preliminary diagnosis influenza. On the fith day of illness he got a maculopapular petechial rash on his body and internal surfaces of extremities. Body temperature is 410 C, euphoria, face hyperemia, sclera reddening, tongue tremor, tachycardia, splenomegaly, excitement. What is the most probable diagnosis?

Correct Answer: A

Rationale: Step 1: Initial diagnosis of influenza suggests a viral illness. Step 2: Presence of maculopapular petechial rash and high fever indicates a systemic infection. Step 3: Symptoms like euphoria, hyperemia, tachycardia, splenomegaly, and excitement are characteristic of epidemic typhus. Step 4: Face hyperemia, sclera reddening, and tongue tremor are specific to epidemic typhus. Step 5: Epidemic typhus is transmitted by body lice, which fits the scenario of a patient without permanent residence. Summary: - Delirium alcoholicum is unlikely due to the specific symptoms and lack of history of alcohol abuse. - Leptospirosis typically presents with jaundice and renal symptoms, not seen in this case. - Measles rash is different from the maculopapular petechial rash described.

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