ATI RN
Microbiology An Introduction 13th Edition Test Bank Questions
Question 1 of 9
In order to establish the possible contamination of a medication with fungi, a nutrient medium was inoculated, which resulted in growth of large cream-like colonies. What nutrient medium was used in this case?
Correct Answer: A
Rationale: The correct answer is A: Sabouraud. Sabouraud agar is specifically designed to promote the growth of fungi due to its low pH and high glucose content. The cream-like colonies indicate fungal growth, as fungi often appear as fluffy or powdery colonies on Sabouraud agar. Lowenstein-Jensen is used for mycobacteria, Roux for diphtheria, and Loeffler for Corynebacterium diphtheriae. Therefore, Sabouraud is the most suitable medium for detecting fungal contamination based on the characteristics of the colonies formed.
Question 2 of 9
Resident microflora is found in:
Correct Answer: B
Rationale: The correct answer is B (Urethra). Resident microflora are typically found in various parts of the body where they establish a stable population without causing harm. The urethra is one of the locations where resident microflora are commonly present, helping to maintain a healthy microbial balance and prevent pathogenic bacteria from colonizing the area. In contrast, choices A, C, and D are not typical locations for resident microflora. Blood is normally sterile, the lungs have a different microbial environment due to their exposure to the external environment, and the cerebro-spinal fluid is also typically sterile to prevent infections in the central nervous system.
Question 3 of 9
Poxviruses are largest viruses, almost visible on light microscope
Correct Answer: A
Rationale: The correct answer is A: TRUE. Poxviruses are indeed the largest viruses known, ranging from 200-450 nm in size, which is close to the resolution limit of a light microscope. This makes them almost visible under a light microscope. Explanation: 1. Poxviruses have complex structures and are among the largest viruses. 2. Light microscopes have a resolution limit of around 200 nm. 3. Poxviruses fall within the size range that is close to the resolution limit of a light microscope. 4. Therefore, poxviruses are almost visible under a light microscope. Summary: Choice B is incorrect because poxviruses are indeed large enough to be almost visible under a light microscope. Choice C is incorrect as it implies uncertainty, but poxviruses are consistently close to the resolution limit of a light microscope. Choice D is incorrect as the size of poxviruses being almost visible under a light microscope is a factual statement, not dependent
Question 4 of 9
A 65 y.o. woman complains of complicated mouth opening following foot trauma 10 days ago. Next day she ate with difficulties, there were muscles tension of back, the back of the head and abdomen. On the third day there was tension of all muscle groups, generalized convulsions every 10-15 min. What is the most probable diagnosis?
Correct Answer: A
Rationale: The most probable diagnosis is Tetanus (Choice A) based on the symptoms described. Tetanus is characterized by muscle stiffness, difficulty opening the mouth (trismus), muscle spasms, and convulsions. The progression of symptoms from muscle tension to generalized convulsions every 10-15 min is classic for tetanus. Tetania (Choice B) is similar but typically presents with more subtle muscle contractions rather than convulsions. Meningoencephalitis (Choice C) presents with fever, headache, and altered mental status, not the muscle symptoms described. Hemorrhagic stroke (Choice D) presents with sudden onset neurological deficits like weakness or sensory changes, not the muscle symptoms described.
Question 5 of 9
As per their chemical structure the endotoxins are:
Correct Answer: A
Rationale: The correct answer is A: Lipopolysaccharides. Endotoxins are a type of bacterial toxin found in the outer membrane of Gram-negative bacteria. They consist of lipid A, which is a lipid component, and polysaccharides, making them lipopolysaccharides. Lipoproteins (choice B) and glycoproteins (choice C) do not accurately describe the chemical structure of endotoxins. "None of the above" (choice D) is incorrect as lipopolysaccharides are indeed the chemical structure of endotoxins.
Question 6 of 9
A 70-year-old man was admitted to the hospital after suffering extensive third-degree burns. Three days later he spiked a fever and there was pus on the dressing that had blue-green colour. Gram stain of the pus revealed gram-negative rods. The most possible cause of these findings is:
Correct Answer: A
Rationale: The correct answer is A: The pyocyanin released by Pseudomonas aeruginosa. Pyocyanin is a blue-green pigment produced by Pseudomonas aeruginosa, a common cause of nosocomial infections in burn patients. The presence of blue-green pus and gram-negative rods in the wound along with fever suggests an infection with Pseudomonas aeruginosa. The other choices are incorrect because E. Coli typically causes gastrointestinal infections and releases enterotoxins, Staphylococcus aureus releases hemolysins causing hemolysis of red blood cells, and Shigella dysenteriae releases shigatoxin causing bloody diarrhea, none of which match the clinical presentation described in the question.
Question 7 of 9
Mycobacterium tuberculosis is
Correct Answer: D
Rationale: The correct answer is D because Mycobacterium tuberculosis is a straight or slightly curved rod with occasional polymorphism. This bacterium does not conform to the characteristics of gram-negative coccus (A), gram-positive coccus (B), or gram-negative rod (C). Mycobacterium tuberculosis is characterized by its unique cell wall composition, which includes high lipid content and mycolic acids, contributing to its acid-fast staining property. The other choices are incorrect because they do not accurately describe the morphology of Mycobacterium tuberculosis.
Question 8 of 9
Which group of drugs can be used to treat influenza?
Correct Answer: D
Rationale: The correct answer is D: Neuraminidase inhibitors. Neuraminidase is an enzyme crucial for the release of new viral particles from infected cells during influenza infection. By inhibiting neuraminidase, the spread of the virus is limited. Protease inhibitors (choice A) are used to treat HIV, not influenza. Beta-lactamase inhibitors (choice B) are used in combination with beta-lactam antibiotics to increase their effectiveness against bacteria, not viruses. Reverse transcriptase inhibitors (choice C) are used to treat HIV by blocking the enzyme responsible for replicating the virus's genetic material, but they are not effective against influenza.
Question 9 of 9
A patient suffering from syphilis was prescribed a drug the action of which based upon disturbed generation of murein leading to death of the causative agent. What drug is it?
Correct Answer: A
Rationale: The correct answer is A: Benzylpenicillin sodium salt. Benzylpenicillin is a beta-lactam antibiotic that inhibits the synthesis of bacterial cell walls by disrupting the formation of murein (peptidoglycan), leading to bacterial cell death. This mechanism specifically targets the causative agent of syphilis, Treponema pallidum. - Choice B: Bijochinol is not a known drug used to treat syphilis. - Choice C: Ciprofloxacin is a fluoroquinolone antibiotic that works by inhibiting bacterial DNA replication and is not the first-line treatment for syphilis. - Choice D: Azithromycin is a macrolide antibiotic that interferes with bacterial protein synthesis and is commonly used to treat other infections but is not the preferred treatment for syphilis.