Impression smear of mucosa biopsy material has been obtained from a patient with peptic ulcer disease of the stomach. Gram-negative arcuate bent microorganisms were detected, urease activity test was positive. What microorganisms were detected in the patient?

Correct Answer: A

Rationale: The correct answer is A: Helicobacter. Helicobacter pylori is the main causative agent of peptic ulcer disease and is characterized by its gram-negative arcuate bent shape and positive urease activity. Helicobacter pylori specifically colonizes the stomach mucosa and is associated with various gastrointestinal disorders. Spirochetes (choice B), spirilla (choice C), and Leptospira (choice D) are not typically associated with peptic ulcer disease or stomach mucosa infections, making them incorrect choices in this context.

Correct Answer: A

Rationale: The likely diagnosis is Meningococcal meningitis (Choice A) due to the presence of Gram-negative diplococci in the cerebrospinal fluid. Neisseria meningitidis is a Gram-negative diplococcus commonly associated with meningococcal meningitis. Fever, chills, and neck stiffness are classic symptoms of bacterial meningitis, and Neisseria meningitidis often presents with these symptoms. Pneumococcal meningitis (Choice B) is caused by Streptococcus pneumoniae, a Gram-positive organism. Haemophilus influenzae (Choice C) is also a Gram-negative organism but typically presents with a different clinical picture. Listeria monocytogenes (Choice D) is a Gram-positive rod and is more commonly associated with meningitis in neonates, elderly, and immunocompromised individuals.

Correct Answer: A

Rationale: Step 1: Mycobacterium leprae is the bacterium responsible for causing leprosy, a chronic infectious disease affecting the skin and nerves. Step 2: Neisseria gonorrhoeae causes gonorrhea, a sexually transmitted infection. Step 3: Streptococcus pneumoniae causes pneumonia and other respiratory infections. Step 4: Clostridium perfringens causes gas gangrene and food poisoning. Summary: A is correct as Mycobacterium leprae specifically causes leprosy, while B, C, and D cause different diseases unrelated to leprosy.

Correct Answer: B

Rationale: Rationale: The correct answer is B. Viruses of the family Paramyxoviridae cause the formation of giant multinucleated cells called syncytia. This occurs when infected cells fuse together, resulting in large, multinucleated structures. This is a characteristic cytopathic effect of paramyxoviruses. Summary: A: Fine grained degeneration is not typically seen in paramyxovirus infections. C: Large cell degeneration with grape clustering of cells is not a typical cytopathic effect of paramyxoviruses. D: Paramyxoviruses do provoke a cytopathic effect, so this statement is incorrect.

Correct Answer: A

Rationale: The correct answer is A: Mantoux test. The Mantoux test is used to detect tuberculosis infection by injecting a small amount of tuberculin under the skin and checking for a reaction. This test helps identify individuals who have been exposed to tuberculosis. The other choices are incorrect because: B: Schick test is used to determine immunity to diphtheria, not tuberculosis. C: Anthraxine test is used for anthrax, not tuberculosis. D: Burnet test is not a recognized medical test for tuberculosis.

Correct Answer: D

Rationale: The correct answer is D because Cytomegalovirus infections are caused by human herpesvirus 5, also known as Human Herpesvirus 5 (HHV-5) or Cytomegalovirus (CMV). This virus belongs to the Herpesviridae family, genus Betaherpesvirinae. Options A, B, and C are incorrect as they do not correspond to the specific virus responsible for causing Cytomegalovirus infections.

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pneumoniae. 1. Gram-positive diplococci with pointed ends: characteristic morphology of Streptococcus pneumoniae. 2. Surrounded by a capsule: S. pneumoniae is encapsulated, important for virulence. 3. Klebsiella pneumoniae (B) is a Gram-negative rod, Neisseria meningitidis (C) is a Gram-negative diplococcus, and Staphylococcus aureus (D) is a Gram-positive cocci in clusters, not diplococci.

Correct Answer: A

Rationale: Step 1: Gram-positive diplococci suggest a pneumococcal infection. Step 2: Catalase-negative indicates Streptococcus. Step 3: Alpha-hemolysis matches S. pneumoniae's characteristics. Therefore, Streptococcus pneumoniae is the most likely causative agent. Staphylococcus aureus (B) is catalase-positive, Neisseria meningitidis (C) is Gram-negative, and Klebsiella pneumoniae (D) is not diplococci or alpha-hemolytic.

Correct Answer: A

Rationale: The presence of flagella in a bacterial cell represents the H-antigen. Flagella are protein structures on the cell surface that play a role in bacterial motility. The H-antigen refers to the flagellar antigen, which is involved in immune responses and bacterial identification. Option A is correct because flagella are specifically associated with the H-antigen. Summarily, choices B and C are incorrect because the O-antigen and K-antigen are associated with lipopolysaccharide and capsule antigens, respectively, not flagella. Option D is incorrect as well because the correct association is with the H-antigen.