Immunity after single vaccination against tetanus - application of tetanus toxoid is:

Correct Answer: B

Rationale: The correct answer is B. Immunity after a single tetanus vaccination is of limited duration, usually around 10 years. Booster vaccinations are needed to maintain protection due to waning immunity over time. Choice A is incorrect as immunity is not usually lifelong. Choice C is incorrect as tetanus toxoid is a sterile vaccine and does not cause infection. Choice D is also incorrect as there is a correct answer, which is B.

Correct Answer: B

Rationale: The correct answer is B: Salmonella enteritidis. Salmonellosis is typically caused by Salmonella species, with Salmonella enteritidis being one of the common culprits. Salmonella typhi causes typhoid fever, not salmonellosis. Shigella flexneri is responsible for causing shigellosis, a different bacterial infection. Choosing "None of the above" is incorrect as Salmonella enteritidis is a known cause of salmonellosis.

Correct Answer: A

Rationale: The correct answer is A: Clostridium tetani. This bacterium is known for causing tetanus due to its ability to produce tetanospasmin, a neurotoxin that leads to the characteristic muscle stiffness and spasms seen in tetanus. Clostridium perfringens (Choice B) is associated with gas gangrene, Streptococcus pyogenes (Choice C) causes streptococcal infections, and Escherichia coli (Choice D) is known for causing various gastrointestinal infections. Therefore, Choices B, C, and D are incorrect as they are not the causative agents of tetanus.

Correct Answer: B

Rationale: The correct answer is B: Malarial plasmodiums. The description of crescent bodies with a pointed end, blue cytoplasm, and red nucleus corresponds to the characteristics of Plasmodium species seen in Romanovsky's stain. Plasmodium species are known to cause malaria and have distinct features like the ones described. Incorrect choices: A: Toxoplasmas - Toxoplasma gondii typically appear as tachyzoites or bradyzoites under staining, not crescent bodies. C: Dermotropic leishmania - Leishmania species appear as amastigotes in tissue smears, not crescent bodies. D: Viscerotropic leishmania - Similar to choice C, Leishmania species do not typically present as crescent bodies in stained specimens.

Correct Answer: B

Rationale: The correct answer is B: protein filaments made of flagellin. Bacterial flagella are composed of flagellin proteins arranged in helical filaments. This structure allows for movement and propulsion of bacteria. A: 9+2 microtubule arrangement is incorrect because this structure is typically found in eukaryotic flagella, not bacterial flagella. C: Lipid bilayer is incorrect as it is a structural component of cell membranes, not bacterial flagella. D: Peptidoglycan layer is incorrect as it is a component of bacterial cell walls, not flagella.

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pyogenes. 1. Gram-positive cocci in chains suggest streptococci. 2. Beta-hemolytic activity indicates Streptococcus pyogenes. 3. Streptococcus pyogenes is commonly associated with sore throat (pharyngitis) and fever. 4. Streptococcus pneumoniae (choice B) is alpha-hemolytic and mainly causes pneumonia. 5. Enterococcus faecalis (choice C) is not typically associated with sore throat. 6. Staphylococcus aureus (choice D) is not commonly beta-hemolytic and is not a typical cause of pharyngitis.

Correct Answer: C

Rationale: The correct answer is C: Increased active efflux from the bacterial cell. This is the most important mechanism of tetracycline resistance because it involves the bacteria actively pumping out the antibiotic, reducing its intracellular concentration. This prevents tetracycline from effectively targeting bacterial ribosomes. Choice A is incorrect as tetracycline resistance typically involves active efflux rather than reduced influx. Choice B is incorrect because tetracycline resistance mechanisms do not primarily involve altered cell membrane components affecting passive influx. Choice D is also incorrect as tetracycline resistance mechanisms do not typically involve direct enzymatic inactivation of the antibiotic.

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pyogenes. 1. Gram-positive cocci in chains: characteristic of Streptococcus species. 2. Catalase-negative: Streptococcus species are catalase-negative. 3. Beta-hemolytic: S. pyogenes is beta-hemolytic on blood agar. Therefore, S. pyogenes fits all these criteria. B: Streptococcus pneumoniae is catalase-negative but alpha-hemolytic, not beta-hemolytic. C: Enterococcus faecalis is catalase-negative, but not typically beta-hemolytic or in chains. D: Staphylococcus aureus is catalase-positive and not in chains.

Correct Answer: D

Rationale: The correct answer is D (All of the above) because all three bacteria listed produce exotoxins that cause severe gastrointestinal illness. Clostridium botulinum produces botulinum toxin causing botulism. Vibrio cholerae produces cholera toxin leading to cholera. Escherichia coli can produce various exotoxins causing different types of severe gastrointestinal illnesses like E. coli O157:H7 causing bloody diarrhea. Therefore, all choices A, B, and C are correct in this case as they all produce exotoxins causing severe gastrointestinal illness.