ATI RN
Chapter 20 The Lymphatic System and Immunity Sample Questions Questions
Question 1 of 5
IgM is the first antibody isotype secreted following activation of a naive B cell. IgM is found at high concentrations in the serum, and is found as a very high molecular weight complex. This high molecular weight complex is composed of:
Correct Answer: D
Rationale: IgM forms a pentamer for high avidity; not mixed isotypes , non-Ig proteins , or complement .
Question 2 of 5
Which of the following statements about the humoral immune response is true?
Correct Answer: B
Rationale: Humoral immunity, via B cells and antibodies, targets pathogens in fluids (e.g., blood, lymph), not T cell activation, cancer, or macrophage antibody production.
Question 3 of 5
genes are responsible for coding for self-proteins.
Correct Answer: B
Rationale: MHC (Major Histocompatibility Complex) genes encode self-proteins for immune recognition, unlike STR, RFLP, or PCR (genetic tools).
Question 4 of 5
Which of the options below completes the following statement: Intracellular expression by innate immune cells is characteristic of.
Correct Answer: D
Rationale: TLR3, TLR7, and TLR9 are intracellular (endosomal), detecting nucleic acids, unlike TLR4, TLR5, etc., which are surface-bound.
Question 5 of 5
Complete the following sentence. During an immune response, the first antibody isotype expressed is.
Correct Answer: D
Rationale: IgM is the first isotype produced in a primary response, expressed on naïve B cells and secreted early.