If a drug is eliminated by first-order kinetics:

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Drugs Affecting the Female Reproductive System NCLEX Quizlet Questions

Question 1 of 5

If a drug is eliminated by first-order kinetics:

Correct Answer: B

Rationale: First-order kinetics means the rate of drug elimination is proportional to its concentration. Clearance value (correct answer B) remains constant because it represents the volume of blood from which the drug is completely removed per unit time. Choice A is incorrect because the amount eliminated per unit time decreases as the drug concentration decreases. Choice C is incorrect as elimination half-life remains constant regardless of the dose. Choice D is incorrect because it takes approximately 4-5 half-lives for a drug to be considered completely eliminated, not just 2.

Question 2 of 5

All of the following about free (unbound) drugs in plasma are true EXCEPT:

Correct Answer: A

Rationale: Step-by-step rationale: 1. Highly bound drugs have minimal drug-drug interactions due to limited free drug concentration. 2. Free drugs can pass through glomerular filtration due to their small size. 3. Free drugs are available for hepatic metabolism as bound drugs are not metabolized. 4. Free drugs can distribute to peripheral tissues as bound drugs are restricted by protein binding. Summary: Choice A is incorrect as highly bound drugs have limited interactions. Choices B, C, and D are correct as free drugs can pass through filtration, undergo hepatic metabolism, and distribute to tissues.

Question 3 of 5

The nurse, working with a preconceptional couple at an infertility clinic, advises the woman to take which supplement for at least 3 months before becoming pregnant?

Correct Answer: C

Rationale: The correct answer is C: Folic acid. Folic acid is crucial for preventing neural tube defects in the fetus. Taking it before conception helps ensure adequate levels during early pregnancy. Iron is important for pregnant women but not necessarily for preconception. Ginger and Vitamin B6 do not have specific benefits related to preconception or pregnancy.

Question 4 of 5

The nurse working in labor and delivery is reviewing messages to be returned to clients. Which statement made by the client alerts the nurse to call that client first?

Correct Answer: B

Rationale: The correct answer is B because taking ibuprofen during pregnancy, especially in the third trimester like at 38 weeks, can pose risks to the baby. Ibuprofen is not recommended in late pregnancy as it can lead to complications such as premature closure of a crucial blood vessel in the baby's heart. Therefore, the nurse should call this client first to educate them on the risks and advise against taking aspirin along with ibuprofen. A: Taking calcium carbonate for heartburn during pregnancy is generally safe, so there is no urgent need to call this client first. C: Stopping folic acid at 8 weeks may not be ideal, but it is less urgent than the potential risks associated with ibuprofen in late pregnancy. D: Blood glucose of 120 mg may be normal, and the client's non-diabetic status indicates less urgency compared to the potential harm from mixing ibuprofen and aspirin during late pregnancy.

Question 5 of 5

A client is to have lumbar epidural anesthesia. Which nursing action is appropriate?

Correct Answer: C

Rationale: The correct answer is C because infusing 500 to 1000 mL of a crystalloid intravenous solution is appropriate to maintain hydration and fluid balance during lumbar epidural anesthesia. This helps prevent hypotension and supports renal function. A: Citric acid/sodium citrate is used to prevent blood clotting during dialysis, not for epidural anesthesia. B: Promethazine is an antiemetic and antihistamine, not indicated for epidural anesthesia. D: Rh0(D) immune globulin injection is used to prevent Rh incompatibility in pregnancy, not relevant to lumbar epidural anesthesia.

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