ATI RN
ATI Capstone Pharmacology Assessment 2 Questions
Question 1 of 5
If a bacteria were susceptible to both penicillin and erythromycin, then it would not be appropriate to treat the patients with both antibiotics at the same time because:
Correct Answer: A
Rationale: Penicillin is inactivated by erythromycin. Penicillin is a beta-lactam antibiotic which acts by inhibiting cell wall synthesis in bacteria. However, erythromycin is a macrolide antibiotic which can inactivate beta-lactam antibiotics like penicillin. When given together, erythromycin can inactivate penicillin, reducing its efficacy and potentially leading to treatment failure. Therefore, it is not appropriate to use both penicillin and erythromycin simultaneously to treat a bacterial infection.
Question 2 of 5
Which of the following is a potassium-sparing diuretic?
Correct Answer: B
Rationale: Spironolactone is a potassium-sparing diuretic that works by blocking the effects of aldosterone in the distal tubules of the kidney, leading to increased excretion of sodium and water while retaining potassium. This class of diuretics helps to conserve potassium, making them suitable for patients at risk of hypokalemia. In contrast, furosemide, hydrochlorothiazide, and bumetanide are loop diuretics, thiazide diuretics, and another loop diuretic, respectively, which all promote the loss of potassium along with sodium and water.
Question 3 of 5
The nurse is caring for a patient receiving IV heparin therapy for treatment of a pulmonary embolus. The patient is being converted to warfarin (Coumadin) therapy. The following questions relate nursing considerations when caring for this patient. Nursing considerations for conversion of IV heparin to oral warfarin (Coumadin) therapy will include
Correct Answer: B
Rationale: When converting a patient from IV heparin to oral warfarin (Coumadin) therapy, overlapping therapy of both medications for at least 5 days is typically recommended. This overlap ensures that the patient's blood remains appropriately anticoagulated during the transition period. The effectiveness of warfarin is delayed and it takes time for the INR to reach the therapeutic range; therefore, it is important to continue the IV heparin until the INR is within the desired range. Monitoring the INR is essential to adjust the dosages of warfarin accordingly and to ensure that the patient is receiving adequate anticoagulation therapy.
Question 4 of 5
Drug action that increase body activity
Correct Answer: A
Rationale: Stimulants are drugs that increase the body's activity levels. They work on the central nervous system to enhance alertness, attention, and energy. Examples of stimulants include caffeine, amphetamines, and nicotine. Stimulants can increase heart rate, blood pressure, and metabolism, leading to heightened physical and mental activity.
Question 5 of 5
Which assessment finding, by the nurse, is a priority concern when a client receives pseudoephedrine (Sudafed)?
Correct Answer: C
Rationale: Pseudoephedrine, an oral decongestant, stimulates alpha-adrenergic receptors, potentially causing cardiovascular effects like dysrhythmias due to its sympathomimetic action. An irregular heart rate of 82 is a priority concern, signaling possible arrhythmia, which could escalate to serious cardiac events, requiring immediate reporting. A mild fever or elevated respiratory rate could relate to the underlying condition (e.g., infection) rather than the drug. Dry mouth is a common, benign side effect. The nurse focuses on the irregular pulse as it aligns with pseudoephedrine's known risk of dysrhythmias, especially in susceptible patients, making choice C the most urgent finding to address.