Huntington’s disease is an example of a genetic disorder caused by:

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Genetic Disorders in Pediatrics Questions

Question 1 of 5

Huntington’s disease is an example of a genetic disorder caused by:

Correct Answer: A

Rationale: Huntington’s is caused by a dominant allele with late onset (typically adulthood), and it is lethal due to progressive neurodegeneration.

Question 2 of 5

Cancer causing agents are called:

Correct Answer: A

Rationale: Carcinogens are agents that cause cancer, distinct from mutagens (cause mutations) or teratogens (cause birth defects).

Question 3 of 5

is a type of cancer-causing gene that promotes cancer by activating cell division at an inappropriate time or place:

Correct Answer: C

Rationale: Oncogenes are mutated proto-oncogenes that drive uncontrolled cell division.

Question 4 of 5

Formation of a retinoblastoma eye tumor requires:

Correct Answer: C

Rationale: Retinoblastoma follows the two-hit hypothesis: a germline mutation in one RB1 allele and a somatic mutation in the other inactivate the tumor suppressor.

Question 5 of 5

Growth of new blood vessels in and around tumors is called:

Correct Answer: B

Rationale: Angiogenesis is the formation of new blood vessels, critical for tumor growth and survival.

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