ATI RN
Genetic Disorders in Pediatrics Questions
Question 1 of 5
Huntington’s disease is an example of a genetic disorder caused by:
Correct Answer: A
Rationale: Huntington’s is caused by a dominant allele with late onset (typically adulthood), and it is lethal due to progressive neurodegeneration.
Question 2 of 5
Cancer causing agents are called:
Correct Answer: A
Rationale: Carcinogens are agents that cause cancer, distinct from mutagens (cause mutations) or teratogens (cause birth defects).
Question 3 of 5
is a type of cancer-causing gene that promotes cancer by activating cell division at an inappropriate time or place:
Correct Answer: C
Rationale: Oncogenes are mutated proto-oncogenes that drive uncontrolled cell division.
Question 4 of 5
Formation of a retinoblastoma eye tumor requires:
Correct Answer: C
Rationale: Retinoblastoma follows the two-hit hypothesis: a germline mutation in one RB1 allele and a somatic mutation in the other inactivate the tumor suppressor.
Question 5 of 5
Growth of new blood vessels in and around tumors is called:
Correct Answer: B
Rationale: Angiogenesis is the formation of new blood vessels, critical for tumor growth and survival.