How would you evaluate the medical effectiveness of Metformin?

Questions 32

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ATI Pharmacology Made Easy 4.0 Questions

Question 1 of 5

How would you evaluate the medical effectiveness of Metformin?

Correct Answer: A

Rationale: To evaluate the medical effectiveness of Metformin, it is essential to monitor serum glucose levels, as Metformin is commonly used to treat type 2 diabetes by decreasing glucose production in the liver and increasing insulin sensitivity in peripheral tissues. Monitoring serum electrolytes, ketones, blood pH, lactate, and pyruvate levels is also important because Metformin can potentially cause lactic acidosis, especially in patients with kidney or liver impairment. By assessing these parameters, healthcare providers can gauge the efficacy and safety of Metformin therapy. Checking for resolution of hypothyroidism and hormone normalization is not directly related to evaluating Metformin's effectiveness. Pain reduction and patient alertness are also not the primary indicators for assessing the medical effectiveness of Metformin in managing diabetes.

Question 2 of 5

What is a high alert nursing implication for Morphine?

Correct Answer: B

Rationale: The high alert nursing implication for Morphine is to assess the level of consciousness, blood pressure, pulse, and respiration. Morphine is a potent opioid analgesic that can cause respiratory depression, sedation, and hypotension as side effects. Monitoring the patient's vital signs and neurological status is crucial to detect any signs of overdose or adverse reactions promptly. Maintaining vigilant observation of these parameters can help prevent serious complications and ensure the safe administration of Morphine.

Question 3 of 5

The following drugs are partial agonists:

Correct Answer: C

Rationale: Buprenorphine is a partial agonist at opioid receptors, providing analgesia with a ceiling effect, reducing risk of respiratory depression.

Question 4 of 5

How would you evaluate the medical effectiveness of Metformin?

Correct Answer: A

Rationale: To evaluate the medical effectiveness of Metformin, it is essential to monitor serum glucose levels, as Metformin is commonly used to treat type 2 diabetes by decreasing glucose production in the liver and increasing insulin sensitivity in peripheral tissues. Monitoring serum electrolytes, ketones, blood pH, lactate, and pyruvate levels is also important because Metformin can potentially cause lactic acidosis, especially in patients with kidney or liver impairment. By assessing these parameters, healthcare providers can gauge the efficacy and safety of Metformin therapy. Checking for resolution of hypothyroidism and hormone normalization is not directly related to evaluating Metformin's effectiveness. Pain reduction and patient alertness are also not the primary indicators for assessing the medical effectiveness of Metformin in managing diabetes.

Question 5 of 5

The physician ordered a loading dose of medication for the patient; it is to be followed by a lower dose. When the patient receives the lower dose, she says to the nurse, 'I think my doctor made a mistake; my medication dose is too low.' What is the best response by the nurse?

Correct Answer: C

Rationale: A loading dose rapidly achieves therapeutic levels, followed by a lower maintenance dose, a standard approach explained clearly here. Half-life isn't shortened-it's about concentration. ‘Always' oversimplifies. Side effect reduction isn't the goal-efficacy is. The larger initial dose's purpose reassures the patient, aligning with pharmacokinetic principles for quick action.

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