How many binding sites there are between Complementarity Determining Regions (CDR) and an antigen on one Fab

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Pediatric Immunization Practice Questions Questions

Question 1 of 5

How many binding sites there are between Complementarity Determining Regions (CDR) and an antigen on one Fab

Correct Answer: D

Rationale: Each Fab has one antigen-binding site, but with 3 CDRs per chain (light and heavy), there are 6 CDRs total contributing to binding.

Question 2 of 5

The adaptive immune system develops from stem cells originating in the

Correct Answer: B

Rationale: Adaptive immunity arises from stem cells in the fetal liver and bone marrow.

Question 3 of 5

The deficiency of the complement component factor D and properdin lead to the recurrent bacterial infection. Which of the following pathway is affected in this condition?

Correct Answer: A

Rationale: Factor D and properdin are specific to the alternative pathway, and their deficiency impairs bacterial clearance.

Question 4 of 5

The interaction of which molecule on the membrane of cells with its ligand signals apoptosis?

Correct Answer: D

Rationale: Fas (CD95) binding to FasL triggers apoptosis, critical in immune regulation.

Question 5 of 5

The complement system plays a key role in the host defense process. Which of the following components of this system is the most important in chemotaxis?

Correct Answer: D

Rationale: C5a is the most potent complement-derived chemoattractant for neutrophils.

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