How does age-related physiological change affect pharmacokinetics in older adults?

Correct Answer: A

Rationale: The correct answer is A because as individuals age, there is a decrease in renal function leading to reduced renal clearance of drugs. This results in a longer drug half-life and potentially increased drug accumulation in the body. Choice B is incorrect as aging often leads to a decrease in hepatic metabolism, not faster metabolism. Choice C is incorrect because aging can actually lead to reduced gastrointestinal absorption due to changes in the gastrointestinal tract. Choice D is incorrect as aging can result in decreased circulation, which may affect drug distribution negatively.

Correct Answer: B

Rationale: Correct Answer: B Rationale: The thymus gland is responsible for producing T-cells, crucial for immune responses. As individuals age, the thymus gland shrinks and becomes less efficient, reducing the production of new T-cells. This decline in T-cell production weakens the immune response in older adults, making them more susceptible to infections. Therefore, choice B is correct. Summary of Incorrect Choices: A: Aging does not increase the production of white blood cells. In fact, the immune system may weaken with age due to a decline in key immune cells. C: Aging does not improve the body's ability to recognize and fight off pathogens. Instead, it often leads to a decline in immune function. D: While some inflammatory responses may increase with age, excessive inflammation can actually be harmful and contribute to age-related diseases, rather than providing protection.

Correct Answer: B

Rationale: The correct answer is B: administer the lowest dose of 2 mg. In older adults, especially the elderly, it is essential to start with the lowest effective dose of medication to minimize the risk of adverse effects. This approach follows the principle of "start low and go slow" when administering medications to older adults due to age-related changes in drug metabolism and increased sensitivity to medications. Administering the lowest effective dose helps to reduce the risk of potential complications such as respiratory depression, sedation, and falls. Choice A (administer the highest dose of 6 mg) is incorrect because starting with the highest dose can increase the risk of adverse effects in older adults. Choice C (avoid the narcotic because of the risk of addiction) is incorrect as it is important to manage pain effectively in post-operative patients, and opioids can be safely used under proper supervision. Choice D (administer the dose only when the client asks for the medication 2 times) is incorrect as pain management should be

Correct Answer: B

Rationale: Step-by-step rationale: 1. Choice B is the correct answer because dime-sized burned areas on the upper inner thigh can be indicative of elder mistreatment, such as neglect or abuse. 2. Burns in unusual areas like the inner thigh raise suspicion as they are not commonly accidental. 3. Elderly individuals may be unable to defend themselves or report abuse, making it crucial for healthcare providers to recognize potential signs. 4. Choices A, C, and D do not directly suggest elder mistreatment but may indicate other health issues or accidents. Summary: Choice B is correct as it presents a specific sign of potential elder mistreatment, while the other choices do not exhibit clear indicators of abuse or neglect.

Correct Answer: B

Rationale: The correct answer is B. Decreased hearing in older individuals can lead to increased danger as they may not be able to hear important warning sounds like smoke or security alarms. This can compromise their safety and well-being. A is incorrect because decreased hearing may lead to increased stressful interactions due to difficulties in communication. C is incorrect because decreased hearing can actually increase danger when driving or walking in traffic as the individual may not be able to hear car horns or other traffic sounds, leading to potential accidents. D is incorrect because decreased hearing can contribute to an increased risk of falls due to decreased awareness of environmental sounds and hazards.