How do antimetabolites exert their cytotoxic effect?

Questions 170

ATI RN

ATI RN Test Bank

ABVD chemotherapy drugs Questions

Question 1 of 5

How do antimetabolites exert their cytotoxic effect?

Correct Answer: D

Rationale: Antimetabolites act as false substrates in nucleic acid synthesis, disrupting DNA and RNA production.

Question 2 of 5

Recrudescence of malaria refers to recurrence of malarial fever due to

Correct Answer: C

Rationale: Recrudescence occurs due to incomplete clearance of erythrocytic schizonts, leading to resurgence of symptoms.

Question 3 of 5

Radical cure of vivax malaria should be attempted in

Correct Answer: D

Rationale: Radical cure for P. vivax (targeting hypnozoites) is advised in sporadic and controlled endemic areas to prevent relapse.

Question 4 of 5

Amodiaquine differs from chloroquine in the following respect(s)

Correct Answer: C

Rationale: Amodiaquine is less bitter and causes less itching than chloroquine, though its use is limited due to toxicity concerns.

Question 5 of 5

Intravenous injection of quinine produces

Correct Answer: D

Rationale: IV quinine can cause hypoglycemia by stimulating insulin release.

Access More Questions!

ATI RN Basic


$89/ 30 days

ATI RN Premium


$150/ 90 days

Similar Questions