Hepatitis C is a virus that infects hepatocytes, which are non-immune cells of the liver. Currently, patients with chronic Hepatitis C infections are treated with repeated administration of type I interferon, predominantly interferon α. One aspect of this treatment that might aid the patient's immune system in clearing this virus infection is:

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Immune System Multiple Choice Questions and Answers PDF Questions

Question 1 of 5

Hepatitis C is a virus that infects hepatocytes, which are non-immune cells of the liver. Currently, patients with chronic Hepatitis C infections are treated with repeated administration of type I interferon, predominantly interferon α. One aspect of this treatment that might aid the patient's immune system in clearing this virus infection is:

Correct Answer: A

Rationale: Type I interferon boosts MHC I on hepatocytes , aiding CD8 T cells; macrophage action or inflammation are less direct.

Question 2 of 5

A molecule that can elicit an adaptive immune response is called

Correct Answer: D

Rationale: An antigen triggers adaptive immunity by being recognized by lymphocytes, unlike complement (innate), interferon (antiviral), or antibodies (response products).

Question 3 of 5

After binding to an infected cell, the cytotoxic T cell

Correct Answer: D

Rationale: Cytotoxic T cells release perforin to lyse infected cells, not interleukin-1, phagocytosis, or neutralization.

Question 4 of 5

Which is the least abundant granulocyte in peripheral blood?

Correct Answer: A

Rationale: Basophils are the least abundant granulocytes in blood (<1%), unlike neutrophils (most abundant) or eosinophils; mast cells reside in tissues.

Question 5 of 5

What is the difference between the recombination of heavy and light chain variable regions?

Correct Answer: B

Rationale: Heavy chains use V, D, and J segments, while light chains use V and J only; both require RAG1/2.

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