ATI RN
Quiz Endocrine Reproductive System & Respiratory Drugs Questions
Question 1 of 5
Health benefits afforded by the combined estrogenprogestin oral contraceptive pill include the following except:
Correct Answer: C
Rationale: While the combined estrogen-progestin oral contraceptive pill offers various health benefits, such as reducing menstrual blood loss, lowering the risk of fibrocystic breast disease, and decreasing the risk of endometrial carcinoma, it is important to note that it is associated with a slightly increased risk of myocardial infarction (heart attack) compared to non-users. This is particularly significant in women who have other risk factors for cardiovascular disease, such as smoking, hypertension, diabetes, or obesity. Overall, the cardiovascular risks should be carefully evaluated and discussed with a healthcare provider before initiating the use of the combined oral contraceptive pill, especially in women with existing cardiovascular risk factors.
Question 2 of 5
In which of the following forms of oral contraception, pills are taken continuously without interruption:
Correct Answer: C
Rationale: The form of oral contraception in which pills are taken continuously without interruption is known as the minipill. Unlike the combined pill, which contains both estrogen and progesterone, the minipill contains only progestin. It is taken daily without any breaks, making it a suitable option for individuals who prefer not to have a menstrual period or have certain medical conditions that may benefit from continuous hormonal contraception.
Question 3 of 5
Which of the following can act as a single dose postcoital contraceptive:
Correct Answer: B
Rationale: Mifepristone, also known as RU-486, is a medication that can act as a single-dose postcoital contraceptive. It is an anti-progestational steroid that can disrupt implantation and early pregnancy by blocking the action of progesterone, an essential hormone for maintaining a pregnancy. Mifepristone is commonly used in combination with misoprostol for medical abortion but can also be used in a lower dose as a postcoital contraceptive option when taken within 72 hours of unprotected intercourse. In contrast, medications like Clomiphene citrate, Danazol, and Medroxyprogesterone acetate are not typically used as emergency contraceptives.
Question 4 of 5
Mifepristone possesses the following activities:
Correct Answer: A
Rationale: Mifepristone, also known as RU-486, is a synthetic steroid that acts as a potent antiprogestin, meaning it blocks the activity of the hormone progesterone. Its antiprogestin activity is the basis for its use in medical abortion and as an emergency contraceptive. Additionally, mifepristone has weak androgenic activity, meaning it may have some effects similar to male sex hormones, such as testosterone. This combination of potent antiprogestin and weak androgenic activities is what distinguishes mifepristone's pharmacological profile.
Question 5 of 5
The 19-Norprogestins differ from progesterone derivatives in that they:
Correct Answer: A
Rationale: The 19-Norprogestins, compared to progesterone derivatives, have potent antiovulatory activity. This means they are highly effective in inhibiting ovulation, making them useful for contraception purposes. They work by suppressing the body's natural hormone production, thereby preventing egg release from the ovary. This fundamental difference sets them apart from progesterone derivatives, which do not exhibit such strong antiovulatory effects.