ATI RN
Microbiology An Evolving Science Test Bank Questions
Question 1 of 5
Granulomas containing lymphocytes and macrophages were detected during analysis of skin biopsy material. Among macrophages there are large cells with fat inclusions, which contain microorganisms in spheric packages (Virchow's cells). The following disease is based on the described type of hypersensitivity:
Correct Answer: C
Rationale: The correct answer is C: Tuberculosis. Granulomas with lymphocytes and macrophages containing Virchow's cells (large cells with fat inclusions containing microorganisms) are classic findings in tuberculosis. Leprosy (A) typically presents with granulomas but with different histopathological features. Syphilis (B) does not usually form granulomas in the skin. Rhinoscleroma (D) is a chronic bacterial infection characterized by nodular lesions but does not typically involve Virchow's cells as seen in tuberculosis.
Question 2 of 5
A wound culture revealed Gram-positive cocci in clusters. The bacteria were catalase-positive and coagulase-negative. What is the most likely microorganism?
Correct Answer: A
Rationale: The correct answer is A: Staphylococcus epidermidis. The presence of Gram-positive cocci in clusters indicates a staphylococcal species. The fact that the bacteria are catalase-positive and coagulase-negative further narrow it down to Staphylococcus epidermidis, as this species fits all the given characteristics. - Choice B, Staphylococcus aureus, is coagulase-positive. - Choice C, Streptococcus pyogenes, is a streptococcal species, not staphylococcal. - Choice D, Enterococcus faecalis, is a Gram-positive cocci but is catalase-negative and not typically found in clusters.
Question 3 of 5
Which of the following antibodies is synthesized by the infant soon after birth?
Correct Answer: B
Rationale: The correct answer is B: IgM. IgM is the first antibody synthesized by the infant soon after birth. It is produced by B cells in response to initial exposure to antigens. IgA is mainly found in mucosal areas, IgG is transferred from mother to fetus, and IgD functions in the early stages of B cell development. Therefore, IgM is the most suitable choice as the antibody synthesized by the infant soon after birth.
Question 4 of 5
A patient with abdominal pain and diarrhea had a stool culture revealing non-lactose-fermenting, Gram-negative rods. What is the most likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Shigella dysenteriae. Shigella causes dysentery, characterized by bloody diarrhea and abdominal pain. Shigella is a non-lactose-fermenting, Gram-negative rod. B: Salmonella typhi causes typhoid fever, not typically associated with abdominal pain and diarrhea. C: Escherichia coli, a common gut bacteria, can cause diarrhea but typically ferments lactose. D: Proteus vulgaris is not a common cause of gastrointestinal infection and is not typically associated with abdominal pain and diarrhea.
Question 5 of 5
A patient with a sore throat and fever had a throat culture revealing Gram-positive cocci in pairs with a capsule. What is the most likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Streptococcus pneumoniae. This bacterium is a Gram-positive cocci that often appear in pairs and can have a capsule. It is a common cause of sore throat and fever, known as streptococcal pharyngitis. Staphylococcus aureus (B) is a Gram-positive cocci but does not typically form pairs. Neisseria meningitidis (C) is a Gram-negative diplococcus and is more associated with meningitis. Klebsiella pneumoniae (D) is a Gram-negative rod and not typically associated with sore throat and fever.
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