Granulocyte colony-stimulating factor (G-CSF) causes an increase in the production of which of the following in the bone marrow?

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Pediatric Immunizations NCLEX Questions Questions

Question 1 of 5

Granulocyte colony-stimulating factor (G-CSF) causes an increase in the production of which of the following in the bone marrow?

Correct Answer: A

Rationale: G-CSF specifically increases neutrophil production.

Question 2 of 5

During B cell development, negative selection occurs in an attempt to ensure the antigen receptor:

Correct Answer: D

Rationale: Negative selection eliminates B cells that bind self-antigens to prevent autoimmunity.

Question 3 of 5

What surface immunoglobulins are present once an immature B cell becomes a mature (peripheral) B cell?

Correct Answer: D

Rationale: Mature B cells express both IgM and IgD on their surface.

Question 4 of 5

Where are single-positive (SP) cells found?

Correct Answer: D

Rationale: SP cells mature in the thymus medulla after positive and negative selection.

Question 5 of 5

CD4+ cells recognize antigen displayed on ___ MHC molecules and CD8+ cells recognize antigen displayed on ___ MHC molecules. ___ has TH1 and TH2 cell populations.

Correct Answer: C

Rationale: CD4+ cells recognize MHC class II, CD8+ cells recognize MHC class I, and CD4+ cells include TH1/TH2 subsets.

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