Graft vs host disease often accompanies transplantation of?

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Pediatric Immunizations NCLEX Questions Questions

Question 1 of 5

Graft vs host disease often accompanies transplantation of?

Correct Answer: C

Rationale: Bone marrow transplantation carries a high risk of GVHD due to the presence of immunocompetent donor T cells.

Question 2 of 5

Defects in Macrophage to kill bacteria that synthesis Catalase; this called?

Correct Answer: A

Rationale: Chronic granulomatous disease results from defective NADPH oxidase, impairing macrophages' ability to kill catalase-producing bacteria.

Question 3 of 5

Matching: Complement deficiency - Recurrent neisserial infection

Correct Answer: A

Rationale: Deficiencies in C5, C6, C7, C8, or C9 impair the membrane attack complex, leading to recurrent Neisseria infections (e.g., meningococcus). Properdin stabilizes the alternative pathway but is less directly linked to neisserial susceptibility compared to terminal complement deficiencies.

Question 4 of 5

Matching: Immunodeficiency - High frequency of autoimmune disorders

Correct Answer: C

Rationale: CVID is associated with a high frequency of autoimmune disorders due to immune dysregulation.

Question 5 of 5

The X-linked lymphoproliferative (XLP) syndrome is classically associated with overwhelming infection with which organism?

Correct Answer: A

Rationale: XLP is classically linked to severe, often fatal Epstein-Barr virus infections due to defective immune regulation.

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