ATI RN
Pediatric Immunization NCLEX Questions Questions
Question 1 of 5
Given that an individual's parents have completely different HLA genes, that individual will have about different class I and II MHC molecules on the surface of certain of their lymphoid cells.
Correct Answer: D
Rationale: With different parental HLA genes, an individual inherits 3 class I (HLA-A, B, C) and 3 class II (HLA-DR, DP, DQ) per parent, totaling about 12 unique MHC molecules.
Question 2 of 5
Has different subtypes
Correct Answer: A
Rationale: IgG has subtypes (e.g., IgG1, IgG2), unlike IgM or IgE.
Question 3 of 5
Penicillin can form a hapten-carrier conjugate with a self-protein that can then act as an immunogen and generate an immunoglobulin antibody, and can cross-react with a number of other antibiotics. This can complicate the treatment of bacterial infections in these patients because they are unable to take the antibiotics necessary to combat the infection.
Correct Answer: C
Rationale: This describes an IgE-mediated allergic response, where penicillin cross-reacts, causing hypersensitivity.
Question 4 of 5
Each polypeptide chain (heavy and light) on immunoglobulin has a variable (V) and constant (C) region. Immunoglobulin chains are encoded by that is/are rearranged during development to assemble a functional gene encoding either a heavy or a light chain.
Correct Answer: C
Rationale: Immunoglobulin genes in B cells are encoded by sets of V, D, and J gene segments that rearrange during development.
Question 5 of 5
If alternative processing uses the second polyadenylation site, then what type of heavy chain mRNA is derived?
Correct Answer: C
Rationale: Using the second polyadenylation site results in δ (delta) heavy chain mRNA, encoding IgD.