Gilbert disease, caused by a mutation of the promoter region of glucuronosyl transferase, is characterized by development of

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Infectious Disease Pediatric Questions

Question 1 of 5

Gilbert disease, caused by a mutation of the promoter region of glucuronosyl transferase, is characterized by development of

Correct Answer: D

Rationale: Gilbert syndrome causes mild indirect hyperbilirubinemia (E) from reduced enzyme activity, not anemia (A), cholestasis (B), kernicterus (C), or organomegaly (D).

Question 2 of 5

Polycythemia is an excessively high hematocrit, which may lead to blood hyperviscosity; it is defined as central hematocrit of

Correct Answer: D

Rationale: Polycythemia is defined as hematocrit ≥65% (D), causing hyperviscosity, per neonatal standards.

Question 3 of 5

Hemorrhagic disease of the newborn (HDN) is prevented by administration of single dose of vitamin K (1 mg)

Correct Answer: D

Rationale: IM vitamin K (D) at 1 mg prevents HDN effectively, per AAP recommendations.

Question 4 of 5

During intrauterine life, hemoglobin concentration increases from 8 to 10 g/dL at 12 weeks to 16.5 to 18 g/dL at

Correct Answer: D

Rationale: Hemoglobin reaches 16.5-18 g/dL at term (40 weeks, D), per fetal hematology.

Question 5 of 5

All the following statements regarding ABO incompatibility are true EXCEPT

Correct Answer: A

Rationale: ABO incompatibility affects firstborns (B), is milder than Rh (C), common (D), and mild (E). It doesn’t worsen with pregnancies (A), unlike Rh.

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