Fresh frozen plasma (FFP) transfusion/replacement is indicated in all the following conditions EXCEPT

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Question 1 of 5

Fresh frozen plasma (FFP) transfusion/replacement is indicated in all the following conditions EXCEPT

Correct Answer: C

Rationale: FFP is indicated for liver disease (A), protein S deficiency (B), preterm clotting issues (D), and vitamin K deficiency (E). TTP (C) requires plasma exchange, not FFP transfusion.

Question 2 of 5

In severe liver disease with prolongation of the bleeding time, the best effective treatment before doing liver biopsy is

Correct Answer: D

Rationale: FFP (D) corrects multiple factor deficiencies and thrombocytopenia in severe liver disease before biopsy, more effective than vitamin K (A, B, C, slow) or DDAVP (E, for platelet dysfunction only).

Question 3 of 5

Arterial thrombosis is the least likely cause of

Correct Answer: D

Rationale: Pulmonary embolism (E) is venous thrombosis-related, unlike stroke (A), limb ischemia (B), renal infarction (C), and MI (D), which are arterial.

Question 4 of 5

A previously healthy 10-month-old boy develops pallor over 2 weeks. Examination is unremarkable except for pallor. Lab tests includes: hemoglobin, 4.9 g/dL; WBC, 6700/mm3; platelets count, 180000/mm3; MCV, 79 fL; reticulocyte count 0.8%; hemoglobin electrophoresis, normal. Of the following, the MOST likely cause for these findings is

Correct Answer: B

Rationale: Severe anemia (Hb 4.9 g/dL), low reticulocytes (0.8%), and normal MCV at 10 months suggest TEC (B), a common self-limiting condition. Pure red cell aplasia (A) is rarer, thalassemia (C) is microcytic, aplastic anemia (D) affects all lines, and parvovirus (E) typically affects hemolytic states.

Question 5 of 5

Which of the following drugs is least likely to cause thrombocytopenia in children?

Correct Answer: B

Rationale: Phenytoin (B) rarely causes thrombocytopenia, unlike valproic acid (A), sulfonamides (C), TMP-SMX (D), and heparin (E), which are well-known culprits.

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