Following surgery, a client is placed on cefotaxime (Claforan). The assessment for possible adverse effects should include observing for

Correct Answer: A

Rationale: Cefotaxime is a third-generation cephalosporin antibiotic commonly used to treat bacterial infections post-surgery. One of its most significant and frequent adverse effects is disruption of the gastrointestinal flora, which can lead to diarrhea, including potentially severe conditions like Clostridioides difficile-associated diarrhea. This makes monitoring for diarrhea a critical nursing action, as it can indicate a serious complication requiring immediate intervention. While headache, constipation, and tachycardia can occur with various medications, they are less commonly associated with cefotaxime compared to diarrhea. Headache might suggest a neurological issue or dehydration, constipation could relate to immobility post-surgery rather than the drug itself, and tachycardia might indicate an allergic reaction or systemic issue, but these are not the primary concerns with this antibiotic. Diarrhea, however, directly correlates with cefotaxime's impact on gut microbiota, making it the priority observation for adverse effects in this scenario, thus supporting choice A as the correct answer.

Correct Answer: D

Rationale: Administering antibiotics through an infected central venous access device (CVAD) is often done to attempt to sterilize the catheter and salvage it, avoiding the need for removal and replacement. This approach is particularly useful for certain types of infections. While peripheral IV administration may be less painful or reduce infiltration risks, the primary goal in this scenario is to treat the infection directly at the source. Therefore, the correct rationale is to sterilize the catheter.

Correct Answer: A

Rationale: One potential adverse effect of antihypertensive drugs, particularly beta-blockers and diuretics, is impotence. Antihypertensive medications can affect sexual function in males by causing erectile dysfunction or impotence due to their mechanism of action on blood vessels and circulation. It is important for the nurse to inform the patient about this possible side effect so that appropriate management strategies or alternative treatment options can be discussed. Impotence can have a significant impact on a patient's quality of life and adherence to medication, so open communication and education are essential in managing this issue.

Correct Answer: B

Rationale: Haloperidol, a typical antipsychotic, causes hypotension less than phenothiazines, so that's not its hallmark. It's highly prone to extrapyramidal side effects (EPS) like dystonia due to strong D2 receptor blockade, a true statement. Arrhythmias (e.g., QT prolongation) occur but aren't its primary issue. Antimuscarinic effects are minimal compared to other antipsychotics. Confusion is possible but not its defining toxicity. EPS prominence drives the need for adjunctive anticholinergics in treatment, a key consideration in schizophrenia management.

Correct Answer: A

Rationale: GTN patches deliver the drug transdermally, bypassing first-pass metabolism and providing systemic therapeutic action.