Following is GABA-A antagonist

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Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions

Question 1 of 5

Following is GABA-A antagonist

Correct Answer: B

Rationale: Bicuculline is a competitive antagonist of GABA-A receptors, blocking inhibitory neurotransmission and potentially inducing seizures.

Question 2 of 5

An endocrine gland that plays an important role in calcium metabolism is the:

Correct Answer: D

Rationale: The parathyroid (choice D) regulates calcium via PTH, increasing blood levels. Pancreas (choice A) manages glucose, adrenals (choice B) stress hormones, thyroid (choice C) metabolism via calcitonin. Parathyroid's calcium role is primary.

Question 3 of 5

Which one of the following drugs is not useful in dysmenorrhea?

Correct Answer: B

Rationale: Colchicine is not used for dysmenorrhea; NSAIDs are preferred.

Question 4 of 5

A 59-year-old man with Parkinson's disease begins a course of bromocriptine in hopes of improving his significant symptoms of cogwheel rigidity and bradykinesia. After being on the medication for 6 months, a renal ultrasound is obtained that reveals bilateral hydronephrosis and elevation of his serum creatinine to 2.5 mg/dL. What is the most likely explanation for these findings?

Correct Answer: C

Rationale: Bromocriptine, a dopamine agonist, can cause retroperitoneal fibrosis, leading to ureteral obstruction and hydronephrosis.

Question 5 of 5

Which of the following antipsychotics (in excess dose) is responsible for cardiac arrhythmias?

Correct Answer: C

Rationale: Thioridazine has been associated with QT prolongation and a higher risk of cardiac arrhythmias.

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