Following diagnosis of initial attack of rheumatic fever (RF), RF is considered 'ACTIVE' if any of the following is present Except:

Correct Answer: D

Rationale: Subcutaneous nodules, while a major criterion for RF, are not a primary indicator of disease activity.

Correct Answer: B

Rationale: At 2 months of age, an infant develops a social, responsive smile in response to pleasurable stimuli.

Correct Answer: D

Rationale: Ethambutol is known to cause dose-dependent optic neuritis, presenting as decreased visual acuity and red-green color blindness.

Correct Answer: D

Rationale: The acellular pertussis vaccine is recommended by the American Academy of Pediatrics beginning at age 6 weeks. Infants are at greater risk for complications of pertussis.

Correct Answer: A

Rationale: Hereditary spherocytosis causes normocytic anemia due to membrane defects, not microcytosis. Microcytic hypochromic anemia results from reduced hemoglobin synthesis, as seen in thalassemia and iron deficiency anemia.