Family Reoviridae does not include:

Correct Answer: B

Rationale: The correct answer is B: Orthomyxovirus type 1. Family Reoviridae includes Orthoreovirus types 1, 2, and 3. Orthomyxovirus belongs to a different family, Orthomyxoviridae. Therefore, B is the correct answer. Orthoreovirus types 1, 2, and 3 are part of the Reoviridae family. Choice A, C, and D are incorrect because they are all part of the Reoviridae family which includes Orthoreoviruses.

Correct Answer: B

Rationale: B cells develop in the bone marrow, not the thymus. Firstly, hematopoietic stem cells in the bone marrow give rise to B cells. They undergo maturation and selection processes in the bone marrow, not in the thymus. Therefore, choice B is false. On the other hand, choices A, C, and D are correct. A is true because B cells with high affinity to self-antigens undergo apoptosis to prevent autoimmunity. C is true since B cells synthesize antibodies which can be displayed on their surface as B cell receptors. D is true because B cells can undergo class switching to produce different types of antibodies based on the immune response requirements.

Correct Answer: B

Rationale: The correct answer is B: Typhoid fever. Typhoid fever is transmitted through the fecal-oral route, meaning the bacteria from an infected person's feces can contaminate food or water and then be ingested by another person. This can lead to infection and illness. The other choices, diphtheria (A), syphilis (C), and spotted fever (D) are not transmitted through the fecal-oral route. Diphtheria is spread through respiratory droplets, syphilis is primarily sexually transmitted, and spotted fever is transmitted through tick bites. Thus, only Typhoid fever aligns with the fecal-oral route of transmission.

Correct Answer: A

Rationale: The correct answer is A: TRUE. The innate immune system is the body's first line of defense against infections and is always active, providing immediate protection without prior exposure to a specific pathogen. It includes physical barriers, such as skin and mucous membranes, and cellular components like phagocytes and natural killer cells. The innate immune response is nonspecific and rapid, providing a crucial initial defense against pathogens. Choice B is incorrect because the innate immune system is always active, even without any prior exposure to pathogens. Choice C is incorrect because the innate immune system is consistently functioning to protect the body, regardless of the situation. Choice D is incorrect as the correct answer is A.

Correct Answer: B

Rationale: The correct answer is B: Macrolides. Listeriosis is typically treated with antibiotics such as Penicillin and ampicillin due to their effectiveness against Listeria monocytogenes. Macrolides, on the other hand, are not first-line agents for listeriosis treatment. They are less effective in treating this bacterial infection compared to Penicillin and ampicillin. Cephalosporins may also be less effective against Listeria monocytogenes compared to Penicillin and ampicillin. Choice D is incorrect as Macrolides are not suitable for listeriosis treatment.