Familial isolated gonadotropin deficiency associated with anosmia is

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Endocrine System Pediatric Questions

Question 1 of 5

Familial isolated gonadotropin deficiency associated with anosmia is

Correct Answer: D

Rationale: Kallmann syndrome (D) features hypogonadotropic hypogonadism and anosmia.

Question 2 of 5

Nonketotic hyperosmolar coma is characterized by the following EXCEPT

Correct Answer: B

Rationale: Nonketotic hyperosmolar coma lacks acidosis (B); it features hyperglycemia (A) and dehydration (C).

Question 3 of 5

Signs of insulin resistance or conditions associated with insulin resistance in T2 DM in children include the following EXCEPT

Correct Answer: D

Rationale: PCOS (E) is associated but not a direct sign of insulin resistance; others (A-D) are.

Question 4 of 5

Inborn errors of metabolism (IEM) are hereditary biochemical disorders caused by single-gene mutations that result in alteration of

Correct Answer: D

Rationale: IEMs result from single-gene mutations altering enzyme function, typically affecting protein structure or production (e.g., enzymes), not chromosomes (A), mitochondria broadly (B), fats (C), or carbohydrates (E) as primary defects.

Question 5 of 5

A 6-year-old boy with eczematoid rash, abnormal face, and prominent maxilla complains from deterioration in school performance, hyperactivity, and seizures for the last 2 years. Of the following, the MOST likely enzymatic deficiency is

Correct Answer: D

Rationale: Phenylalanine hydroxylase deficiency (PKU) causes mental decline, seizures, rash, and facial changes from phenylalanine buildup, unlike lysosomal deficiencies (A, B, C) or tyrosinemia (E).

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