ATI RN
Pediatric Immune Disorder Test Questions Questions
Question 1 of 5
Failure to thrive, diarrhea, malabsorption, and infections with opportunistic infections (i.e., fungi, Candida sp, Pneumocystis jiroveci [carinii]) suggest
Correct Answer: C
Rationale: T-cell defects lead to impaired cellular immunity, increasing susceptibility to opportunistic infections like fungi and Pneumocystis jiroveci.
Question 2 of 5
Which of the following Antibodies occurs as a pentameric structure?
Correct Answer: A
Rationale: IgM is the only antibody that naturally occurs as a pentamer, consisting of five monomeric units linked by a J chain, enhancing its ability to bind multiple antigens simultaneously.
Question 3 of 5
Endothelial cells expresses glycoprotein that binds with low affinity to WBCs and helps in their recruitment from blood to tissues
Correct Answer: A
Rationale: E-selectin on endothelial cells binds to sialyl Lewis X on leukocytes, facilitating low-affinity rolling during recruitment.
Question 4 of 5
A medical student wants to perform a study on MACROPHAGES type 1, the best way to get these cells is by
Correct Answer: C
Rationale: M1 macrophages are pro-inflammatory and induced by IFN-γ and LPS stimulation of monocytes, not IL-10 (which promotes M2). Answer provided as C based on immunology.
Question 5 of 5
which of the following cells is not from a myeloid origin
Correct Answer: C
Rationale: NK cells are lymphoid, not myeloid; others (macrophages, neutrophils, mast cells) are myeloid-derived.