Factors for transmission of nosocomial infections are:

Correct Answer: D

Rationale: The correct answer is D because all the factors listed can contribute to the transmission of nosocomial infections. Medical dressings can harbor pathogens, breast milk can be a source of infection if not handled properly, and toys can serve as fomites for spreading germs. Choosing any other option would be incorrect as they all play a role in facilitating the transmission of nosocomial infections. It is important to consider all potential sources of infection in healthcare settings to effectively prevent the spread of nosocomial infections.

Correct Answer: C

Rationale: The correct answer is C: Anti-measles IgM. During acute measles infection, the body produces IgM antibodies specific to the measles virus. This indicates a recent or current infection. A: Anti-mumps IgM and B: Anti-rubella IgM are specific to mumps and rubella viruses, respectively, not measles. D: Anti-CMV IgM is specific to cytomegalovirus, not measles. In summary, choice C is correct because Anti-measles IgM is the specific antibody indicating acute measles infection, while the other choices are antibodies related to different viruses.

Correct Answer: D

Rationale: Production of auto-antibodies can be due to various factors. Mutant B cell clones can lead to the production of self-reactive antibodies. Antibodies against hidden tissues can also trigger autoimmune responses. Genetic factors play a crucial role in predisposing individuals to autoimmunity. Therefore, the correct answer is D, as all these factors can contribute to the production of auto-antibodies. Choice A is incorrect as it only addresses one possible cause. Choice B is incorrect as it focuses solely on antibodies against hidden tissues. Choice C is incorrect as it overlooks the other potential reasons for auto-antibody production.

Correct Answer: A

Rationale: The correct answer is A: Isoniazid and rifampicin. These drugs are considered first-line treatment for tuberculosis due to their high efficacy and low toxicity. Isoniazid targets the cell wall of the tuberculosis bacteria, while rifampicin inhibits RNA synthesis. They are recommended by WHO as the first choice for treating tuberculosis. Choice B (Penicillin and erythromycin) is incorrect because these antibiotics are not effective against tuberculosis bacteria. Choice C (Trimethoprim and third generation cephalosporins) is incorrect because they are not considered first-line drugs for tuberculosis treatment. Choice D (All the listed above can be used depending on their resistance profile) is incorrect because only isoniazid and rifampicin are universally recognized as first-line drugs for tuberculosis regardless of resistance profile.

Correct Answer: B

Rationale: The correct answer is B: Before antibiotic therapy is begun. Detecting penicillin-resistant, beta-lactamase-producing strains before antibiotic therapy is crucial to ensure proper treatment. If detected after therapy (choice A), it may lead to treatment failure. Detection during therapy (choice C) may result in delayed or ineffective treatment. Choice D is incorrect as early detection is essential for successful management.