Correct Answer: D

Rationale: The correct answer is D because all the factors listed can contribute to the transmission of nosocomial infections. Medical dressings can harbor pathogens, breast milk can be a source of infection if not handled properly, and toys can serve as fomites for spreading germs. Choosing any other option would be incorrect as they all play a role in facilitating the transmission of nosocomial infections. It is important to consider all potential sources of infection in healthcare settings to effectively prevent the spread of nosocomial infections.

Correct Answer: A

Rationale: Rifampicin is the correct answer because it inhibits RNA transcription in mycobacteria by binding to the bacterial RNA polymerase. This prevents the synthesis of RNA, leading to the inhibition of protein production essential for bacterial growth. Isoniazid inhibits mycolic acid synthesis, Streptomycin inhibits protein synthesis, and Ethionamide disrupts mycolic acid synthesis. These mechanisms are different from inhibiting RNA transcription, making them incorrect choices.

Correct Answer: A

Rationale: The correct answer is A: Isoniazid and rifampicin. These drugs are considered first-line treatment for tuberculosis due to their high efficacy and low toxicity. Isoniazid targets the cell wall of the tuberculosis bacteria, while rifampicin inhibits RNA synthesis. They are recommended by WHO as the first choice for treating tuberculosis. Choice B (Penicillin and erythromycin) is incorrect because these antibiotics are not effective against tuberculosis bacteria. Choice C (Trimethoprim and third generation cephalosporins) is incorrect because they are not considered first-line drugs for tuberculosis treatment. Choice D (All the listed above can be used depending on their resistance profile) is incorrect because only isoniazid and rifampicin are universally recognized as first-line drugs for tuberculosis regardless of resistance profile.

Correct Answer: D

Rationale: The correct answer is D because all the factors listed can contribute to the transmission of nosocomial infections. Medical dressings can harbor pathogens, breast milk can be a source of infection if not handled properly, and toys can serve as fomites for spreading germs. Choosing any other option would be incorrect as they all play a role in facilitating the transmission of nosocomial infections. It is important to consider all potential sources of infection in healthcare settings to effectively prevent the spread of nosocomial infections.

Correct Answer: A

Rationale: The correct answer is A: Mycobacterium tuberculosis. This bacterium is responsible for causing tuberculosis. It is a slow-growing, acid-fast bacillus that primarily affects the lungs. Mycobacterium tuberculosis is transmitted through the air via respiratory droplets. Choice B, Streptococcus pneumoniae, is a common cause of pneumonia but not tuberculosis. Choice C, Salmonella enterica, causes food poisoning. Choice D, Neisseria meningitidis, causes meningitis, not tuberculosis. Therefore, Mycobacterium tuberculosis is the correct answer based on its characteristics and mode of transmission.