Fab Fragment?

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Pediatric Immunization NCLEX Questions Questions

Question 1 of 5

Fab Fragment?

Correct Answer: C

Rationale: The Fab fragment, produced by papain digestion, retains the antigen-binding site of an antibody, consisting of one light chain and part of a heavy chain.

Question 2 of 5

Anaphylaxis can be triggered by cross-linking of IgE receptors on...?

Correct Answer: D

Rationale: Anaphylaxis is triggered by allergen-induced cross-linking of IgE on mast cells, leading to degranulation and histamine release.

Question 3 of 5

Which one of the following sets of cells can present antigen to helper T cells?

Correct Answer: A

Rationale: B cells and dendritic cells are professional antigen-presenting cells (APCs) that express MHC class II and present antigens to helper T cells.

Question 4 of 5

Matching: Complement deficiency - Fatal meningococcal infection in males

Correct Answer: D

Rationale: Properdin deficiency, an X-linked condition affecting males, impairs the alternative complement pathway, increasing susceptibility to fatal meningococcal infections. Terminal complement deficiencies (C5-9) also cause neisserial infections but are not sex-linked.

Question 5 of 5

Matching: Immunodeficiency - Lymphopenia plus severe neutropenia

Correct Answer: C

Rationale: Reticular dysgenesis is a severe condition with both lymphopenia and neutropenia due to failure of lymphoid and myeloid precursors.

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