ATI RN
Pediatric Immunization NCLEX Questions Questions
Question 1 of 5
Eventual elimination of antigen
Correct Answer: C
Rationale: The effector phase is when activated immune cells eliminate the antigen.
Question 2 of 5
Given that an individual's parents have completely different HLA genes, that individual will have about different class I and II MHC molecules on the surface of certain of their lymphoid cells.
Correct Answer: D
Rationale: With different parental HLA genes, an individual inherits 3 class I (HLA-A, B, C) and 3 class II (HLA-DR, DP, DQ) per parent, totaling about 12 unique MHC molecules.
Question 3 of 5
The aim of monoclonal antibody production is to produce cells that only secrete immunoglobulin directed against the antigen used in immunization. Which of the following hybridoma production steps is NOT correct?
Correct Answer: C
Rationale: Selective medium (e.g., HAT) allows only fused hybridoma cells to survive, not non-fused cells, making c incorrect.
Question 4 of 5
Has different subtypes
Correct Answer: A
Rationale: IgG has subtypes (e.g., IgG1, IgG2), unlike IgM or IgE.
Question 5 of 5
Penicillin can form a hapten-carrier conjugate with a self-protein that can then act as an immunogen and generate an immunoglobulin antibody, and can cross-react with a number of other antibiotics. This can complicate the treatment of bacterial infections in these patients because they are unable to take the antibiotics necessary to combat the infection.
Correct Answer: C
Rationale: This describes an IgE-mediated allergic response, where penicillin cross-reacts, causing hypersensitivity.