Etiological factors for the infectious diseases are often microorganisms with various ultrastructure. Which of the following microorganism groups relates to the eukaryotes?

Correct Answer: A

Rationale: The correct answer is A: Protozoa. Protozoa are eukaryotic microorganisms, meaning they have a true nucleus and membrane-bound organelles. This relates to the question as eukaryotes are organisms with complex cells containing these features. Viruses (B) are non-living entities that require a host cell to replicate, lacking cellular structures. Viroids (C) are smaller than viruses and consist of only RNA, lacking a protein coat. Prions (D) are misfolded proteins causing diseases but are not considered microorganisms nor do they have cellular structure. Thus, protozoa are the only eukaryotic microorganism group among the options.

Correct Answer: B

Rationale: Step-by-step rationale for choice B being correct: 1. The conclusion should be based on evidence or observations. 2. "Doubtful" suggests uncertainty, indicating lack of definitive safety. 3. Choice A is too absolute without considering potential risks. 4. Choice C uses extreme language without proper evidence. 5. Choice D is overly definitive without considering varying levels of contamination. Therefore, choice B is the most reasonable conclusion.

Correct Answer: B

Rationale: The correct answer is B because viruses can indeed be cultured on hen embryos, cell cultures, and experimental animals in vitro. This method allows for the replication and study of viruses outside the host organism. Option A is incorrect as viral cultivation is possible in laboratory settings. Option C is incorrect because while viruses can be grown on nutrient media, it is not the only method. Option D is incorrect as viruses can be cultured in various types of cell cultures, not just human embryonic ones.

Correct Answer: B

Rationale: The correct answer is B: Mycobacterium tuberculosis. This bacterium is responsible for causing tuberculosis. Mycobacterium leprae (choice A) causes leprosy, not tuberculosis. Streptococcus pneumoniae (choice C) is known for causing pneumonia, not tuberculosis. Neisseria gonorrhoeae (choice D) is responsible for causing gonorrhea, not tuberculosis. Mycobacterium tuberculosis is the specific bacterium associated with tuberculosis due to its ability to infect the lungs and other organs, leading to the characteristic symptoms of the disease.

Correct Answer: A

Rationale: The correct answer is Amebiasis. The patient's symptoms of abdominal pain, loose stools with mucus and blood, along with the presence of protozoa containing phagocytosed erythrocytes in stool analysis are indicative of Entamoeba histolytica infection. The size (30-40 microns) and pseudopodia characteristics match E. histolytica. Amebiasis commonly presents with dysentery, while Leishmaniasis (B) typically causes skin ulcers. Trichomoniasis (C) is a sexually transmitted infection, not associated with the described symptoms. Giardiasis (D) is characterized by foul-smelling diarrhea and steatorrhea, not bloody diarrhea as seen in this case.

Correct Answer: B

Rationale: The correct answer is B: rheumatic fever. Rheumatic fever is an inflammatory disease that can occur as a complication following a group A streptococcal infection. This is known as a post-streptococcal complication. It typically affects the heart, joints, skin, and brain. Endocarditis (choice A) is also a complication of streptococcal infections, but it is an infection of the heart valves, not an inflammatory disease like rheumatic fever. Nephritis (choice C) is inflammation of the kidneys and is not directly related to streptococcal infections. Cytomegalovirus (choice D) is a different viral infection and is not associated with streptococcal infections.

Correct Answer: D

Rationale: The correct answer is D, All of the above. Clostridium botulinum produces botulinum toxin causing botulism, Vibrio cholerae produces cholera toxin leading to severe diarrhea, and certain strains of Escherichia coli produce toxins causing gastrointestinal illness. Each bacterium has specific exotoxins that can result in severe gastrointestinal symptoms. Therefore, all three choices are correct in producing exotoxins that can cause severe gastrointestinal illness.

Correct Answer: A

Rationale: The correct answer is A: Selective toxicity. Chemotherapy aims to target cancer cells while minimizing harm to healthy cells, known as selective toxicity. This principle is crucial to effectively treat cancer without causing excessive damage to the patient's body. Accumulation in the macroorganism (B) and causing allergies (C) are not fundamental principles of chemotherapy and can lead to harmful side effects. Therefore, the correct answer is A as it aligns with the core objective of chemotherapy.

Correct Answer: B

Rationale: The correct answer is B: Inactivation. In this method, the sputum sample is processed with a solution of caustic soda, which helps to kill any contaminants present and preserve the tuberculosis bacillus for microscopic examination. This step is crucial in ensuring accurate detection of the bacillus. A: Homogenization involves breaking down the sample to make it uniform, but it does not necessarily involve using caustic soda for inactivation. C: Flotation is a method used to separate different components based on their density and is not specific to inactivating tuberculosis bacillus. D: Filtration involves passing a sample through a filter to separate particles based on size and is not related to inactivating the tuberculosis bacillus.