ATI RN
Chemotherapy drugs Questions
Question 1 of 5
Ethambutol is not used in children below 6 years of age because
Correct Answer: C
Rationale: Ethambutol’s visual toxicity (optic neuritis) is hard to detect in young children, who cannot reliably report symptoms.
Question 2 of 5
Corticosteroids are absolutely contraindicated in which of the following types of tuberculosis
Correct Answer: B
Rationale: Corticosteroids are contraindicated in meningeal TB without anti-TB therapy, as they can worsen the infection; they may be used adjunctively in other types.
Question 3 of 5
The most important dose dependent toxicity of dapsone is
Correct Answer: B
Rationale: Hemolysis is the most significant dose-dependent toxicity of dapsone, especially in G6PD-deficient patients.
Question 4 of 5
The newer lipid formulations of amphotericin B differ from the conventional formulation in the following respects except
Correct Answer: A
Rationale: Newer lipid formulations are not more efficacious but are less toxic (nephrotoxicity, acute reactions) than conventional amphotericin B.
Question 5 of 5
Choose the azole antifungal drug which is used only topically
Correct Answer: D
Rationale: Econazole is used only topically for superficial fungal infections, unlike the others which have systemic uses.