ATI RN
Pharmacology CNS Drugs Quizlet Questions
Question 1 of 5
Estrogen partial agonist used in infertility is:
Correct Answer: C
Rationale: Clomiphene (choice C), an estrogen partial agonist (SERM), induces ovulation in infertility by blocking hypothalamic estrogen receptors, increasing FSH/LH. Anastrozole (choice A) inhibits aromatase, Raloxifene (choice B) treats osteoporosis, Cyproheptadine (choice D) is an antihistamine. Clomiphene's role is specific.
Question 2 of 5
Which of the following antidiabetic drugs is most suitable for treatment of diabetes during pregnancy?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
A 33-year-old man is noted to have tachycardia, heat intolerance, weight loss, and an enlarged thyroid gland. Which of the following is the probable ultimate treatment for this patient?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
A 54-year-old obese patient with type 2 diabetes and a history of alcoholism, he should not receive metformin because it can increase the risk of:
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
Clomiphene acts to induce ovulation by which of the following mechanisms?
Correct Answer: A
Rationale: Clomiphene (choice A), a selective estrogen receptor modulator (SERM), induces ovulation by blocking estrogen receptors in the hypothalamus and pituitary, diminishing negative feedback. This increases gonadotropin (FSH/LH) release, stimulating ovarian follicle development, crucial for infertility treatment. Increasing ERa action (choice B) or amount (choice C) would suppress gonadotropins, countering its purpose. Decreasing gonadotropin secretion (choice D) is the opposite effect, as clomiphene boosts it. By disrupting estrogen's inhibitory signal, clomiphene mimics a low-estrogen state, prompting the pituitary to enhance ovulation. This mechanism distinguishes it from other fertility drugs, highlighting its role in anovulatory conditions like polycystic ovary syndrome, where precise hormonal manipulation is key to success.